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Ultrasound may spot rare nerve disease CANVAS

NCT ID NCT05095870

Diagnosis Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether ultrasound of the nerves can help diagnose CANVAS, a rare genetic disorder that causes balance problems, nerve damage, and dizziness. Researchers measured nerve size in 35 people with confirmed CANVAS and compared them to healthy individuals. The goal was to see if smaller nerves on ultrasound could be a reliable sign of the disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

35 people

The number who actually took part.

Started

Oct 2021

Finished

Mar 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

consecutive patients with CANVAS syndrome followed in our neurology department, using conventional electrophysiology and peripheral nerve ultrasound.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

CANVAS Patients : Inclusion Criteria: * Patients followed at the University Hospital of Nîmes between 2018-2021 * Age \> 18 years * Diagnosis of CANVAS with genetic evidence (RFC1+) * Diagnosis of neuronopathy Exclusion Criteria: * Age \<18 years * Chronic polyradiculoneuritis or other demyelinating neuropathy Control group, inclusion criteria : Patient with axonal sensory-motor or pure sensory neuropathy confirmed by electro neuromyography, and concordant with the clinic.

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Conditions

The condition(s) this trial relates to.

cerebellar ataxia cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome neurodegenerative disease peripheral neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebellar ataxia Neurodegenerative diseases Neuropathy

Contacts and locations

Locations

  • CHU de Nîmes

    Nîmes, 30129, France

More trials for these conditions

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