NEUROPATHY

This study looks at whether a spinal cord stimulator can reduce pain and improve blood vessel health in people with type 2 diabetes who have nerve pain in their legs. About 25 adults with diabetes for over a year and poor circulation will get the device. Researchers will check pa…

This study tests whether a 12-week online tai chi program is practical and helpful for cancer survivors who have nerve damage from chemotherapy. About 21 adults who finished chemo at least 3 months ago and have balance issues or numbness will try the program from home. The goal i…

This study tests a prescription laser device for home use to temporarily relieve foot pain caused by nerve damage (idiopathic peripheral neuropathy). About 32 adults with constant foot pain for at least 3 months will use the device and report their pain levels over 6 weeks. The g…

This small pilot study tests whether using a hand-held vibration device for just 3 minutes each day can safely reduce nerve pain and numbness caused by chemotherapy. Sixteen adults who finished certain chemo drugs at least 60 days ago will try the therapy at home. The main goal i…

This study tests a non-invasive treatment called transcutaneous pulsed radiofrequency for people with postherpetic neuralgia, a chronic nerve pain that can last for years after a shingles rash heals. The treatment uses mild electrical pulses through the skin to reduce pain. The t…

This study aims to understand why some people develop nerve pain after a spinal cord injury. Researchers will use pain tests, brain activity measurements, and body responses like sweating and heart rate to learn more. The study involves 300 adults with spinal cord injuries or per…

This study looks at how nerves change in people who develop nerve damage from the chemotherapy drug cisplatin. Researchers will use a special nerve test to measure these changes in 60 adults starting cisplatin treatment. The goal is to better understand the condition and find ear…

This study will enroll 200 adolescents and adults with cystic fibrosis-related diabetes (CFRD) to find out how common complications like eye, kidney, and nerve problems are. Researchers will also check blood pressure and cholesterol. The goal is to better understand these risks a…

This study is gathering information from 4,000 adults diagnosed with peripheral neuropathy, a condition that affects nerves outside the brain and spinal cord. Researchers will collect data from routine checkups, including clinical exams, nerve tests, and ultrasound images. The go…

This study looks at DNA from 575 breast cancer patients to find genetic changes that increase the risk of nerve damage (peripheral neuropathy) from the chemotherapy drug paclitaxel. Researchers compare patients who had severe nerve damage to those who had none, searching for rare…

This study gathers medical information from 200 adults with nerve or muscle problems who are not already in other NIH studies. Researchers will perform standard tests like nerve studies, ultrasounds, and sweat measurements to create a database for future research. The goal is to …

This study looks at how a drug called enfortumab vedotin affects the nerves of people with advanced bladder cancer that has spread. Researchers will measure nerve function with simple tests before and during treatment. The goal is to better understand nerve damage caused by the d…

This study is gathering information from 1,000 intensive care patients to learn what normal pupil measurements look like when using a special device called a pupillometer. The goal is to create a standard set of values for pupil size and reactivity, which can help doctors better …