NEUROPATHY

This study is testing if a temporary spinal cord stimulator can help people with type 2 diabetes who have painful nerve damage in their legs. Researchers want to see if the device not only reduces pain but also improves blood circulation and artery health in the lower limbs. The …

This small pilot study is testing whether a simple, daily 3-minute hand-held vibration therapy is safe and practical for reducing nerve pain in the hands caused by chemotherapy. Researchers want to see if this approach can ease symptoms and improve quality of life for cancer surv…

This study is testing a non-invasive skin patch that delivers gentle electrical pulses to try to reduce chronic nerve pain caused by shingles, known as postherpetic neuralgia. It will involve 35 adults who still have pain despite standard treatments. Researchers will check if the…

This study is testing whether a 12-week virtual Tai Chi program is a practical and acceptable way to help cancer survivors manage nerve pain and balance problems caused by chemotherapy. About 21 participants with these symptoms will be randomly assigned to either start the Tai Ch…

This study is testing whether a prescription laser device, used at home, can temporarily relieve foot pain caused by unexplained nerve damage (idiopathic peripheral neuropathy). About 32 adults with ongoing foot pain will use the laser themselves for six weeks. Researchers will m…

This study aims to better understand and diagnose peripheral nerve disorders by collecting detailed information from 4,000 patients. Participants will undergo standard nerve tests and ultrasound scans during their regular doctor visits. Researchers will analyze this data to learn…

This study aims to understand why some breast cancer patients develop nerve damage (peripheral neuropathy) from the chemotherapy drug paclitaxel, while others do not. Researchers will analyze the stored DNA of 575 patients who previously received this treatment. By looking for ge…

This study aims to understand why severe nerve pain develops after a spinal cord injury. Researchers will measure pain signals and nervous system responses in 300 participants, including people with recent or long-term injuries and healthy volunteers. The goal is to learn about t…

This study aims to collect data on pupil size and reactions in 1,000 patients in intensive care units. Researchers are using a special device called a pupillometer to take these measurements. The goal is to establish what 'normal' pupil readings look like in very sick patients, w…

This study aims to understand how a bladder cancer drug called enfortumab vedotin affects patients' nerves. Researchers will follow 50 adults with advanced bladder cancer who are starting this treatment. They will use nerve tests to measure changes over 12-15 weeks to learn about…

This study aims to understand how common diabetes-related complications are in people with cystic fibrosis who have had diabetes for at least five years. Researchers will examine 200 adolescents and adults to check for eye, kidney, and nerve problems, as well as heart disease ris…

This study aims to collect standard medical test data from adults with nerve or muscle disorders who are visiting the NIH for evaluation. Researchers will perform tests like nerve conduction studies and muscle ultrasounds during 1-2 visits. The data will be stored in a secure dat…