Can tai chi ease chemo nerve damage? small study aims to find out
NCT ID NCT06807294
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 12-week virtual tai chi program is practical and acceptable for cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN), which causes pain, numbness, and balance problems. Researchers plan to enroll 21 participants who have completed chemotherapy and have ongoing nerve symptoms. The goal is to see if people can stick with the program and find it helpful, not yet to prove it works.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Tai Chi program
- What this could lead to
- If successful, this could offer a gentle, accessible way to manage nerve pain and balance issues after chemotherapy.
- What could go wrong
- This is a very small feasibility study with only 21 participants, so results may not apply broadly. It tests whether the program is practical, not whether it works.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 21 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years old and older * Cancer survivors with no evidence of disease (cancer); * Completed neurotoxic chemotherapy, i.e., platinum agents, taxanes, vinca alkaloids, and bortezomib, at least three months before enrollment; * A CIPN diagnosis based on symptom history, loss of deep tendon reflexes, or presence of symmetrical stocking-glove pain, numbness, or paresthesia; * Answers "yes" to the following question: "Do you feel as though your balance is affected from experiencing CIPN?" or "Are you afraid of falling as a result of your CIPN?"; * On a stable regimen (no change in past three months) if taking anti-neuropathy or other pain medications; * Eastern Cooperative Oncology Group (ECOG) Performance Status Scale score ≤ 2 * Willing to adhere to all study-related procedures, including randomization to the Tai Chi or waitlist group, 2 in-person visits to Dana-Farber Cancer Institute (DFCI) (one within 2 weeks of enrollment and one at week 12); * Willing to adhere to requirement that no new pain medication be taken throughout the study period; and * Individuals receiving endocrine therapy or targeted/antibody therapy, such as trastuzumab, pertuzumab, or immunotherapy, will be eligible to participate. Exclusion Criteria: • Patients who have received physical therapy or Tai Chi training, specifically for CIPN, in the past three months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can ozone gas ease Chemo's lasting numbness?
- Chilling out Chemo's side effects: could cold therapy shield nerves?
- Could simple exercises rebuild strength after chemotherapy nerve damage?
- Acupuncture vs. sham needles: a test for chemo nerve damage
- Video analysis could personalize rehab for chemo nerve damage
- Brain training and nerve stretching could ease chemo nerve damage