Healthy volunteers help doctors understand vein collapse
NCT ID NCT01644760
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how the inferior vena cava, a large vein returning blood to the heart, changes size with breathing in 52 healthy volunteers. Researchers used ultrasound to measure the vein's diameter and diaphragm movement during controlled breaths. The goal was to find a breathing-related threshold that predicts a 50% collapse of the vein, which could help doctors assess fluid status in patients.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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52 people
The number who actually took part.
- Start date
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Sep 2012
- Finished
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Sep 2012
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The volunteer must have given his/her informed and signed consent * The volunteer must be insured or beneficiary of a health insurance plan Exclusion Criteria: * The volunteer is participating in another study * The volunteer is in an exclusion period determined by a previous study * The volunteer is under judicial protection, under tutorship or curatorship * The volunteer refuses to sign the consent * It is impossible to correctly inform the volunteer * The patient is pregnant, parturient, or breastfeeding * The volunteer has known heart disease like heart failure, cardiac arrhythmia * The volunteer takes cardiotropics * The volunteer has known lung disease: obstructive or restrictive respiratory failure * The volunteer has clinical signs of COPD (coughing with morning sputum in a smoking subject) * Any emergency situation
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, 30029, France