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Timing is everything: fluid response in septic shock may change in minutes

NCT ID NCT02116413

First seen Nov 19, 2025 · Last updated May 24, 2026 · Updated 22 times

Summary

This study looked at 145 people with septic shock to see if the timing of checking fluid effectiveness changes results. Patients received 500 ml of fluid over 10 minutes, and doctors checked if they responded right away and again 20 minutes later. The goal was to see how many patients who initially improved later showed no benefit, helping refine treatment timing.

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Contacts and locations

Locations

  • APHM - Hôpital Nord

    Marseille, 13915, France

  • CHRU de Nîmes - Hôpital Universitaire Carémeau

    Nîmes, 30029, France

  • CHU d'Amiens - Hôpital Nord

    Amiens, 80054, France

  • CHU de Besançon - Hôpital Jean Minjoz

    Besançon, 25030, France

  • CHU de Caen - Hôpital Côte de Nacre

    Caen, 14033, France

  • CHU de Clermont Ferrand - Hôpital Estaing

    Clermont-Ferrand, 63003, France

  • CHU de Clermont Ferrand - Hôpital Gabriel-Montpied

    Clermont-Ferrand, 63003, France

  • CHU de Nantes - Hôpital Guillaume et René Laennec

    Nantes, 44093, France

  • CHU de Nice - Hôpital St-Roch

    Nice, 06001, France

Conditions

Explore the condition pages connected to this study.