HEART FAILURE

This study tested a drug called tovinontrine in 303 adults with chronic heart failure where the heart pumps normally but is stiff. The goal was to see if the drug lowers a key heart stress marker (NT-proBNP) compared to a placebo over 12 weeks. Participants had symptoms like shor…

This study tested a newer pacing method (left bundle branch area pacing) against the standard method (right ventricular pacing) in 486 adults with heart block. The goal was to see if the newer method better preserves heart function and reduces risks like heart failure or death. P…

This study tested the safety and effectiveness of sacubitril-valsartan in 60 adults with heart failure and reduced pumping ability. The goal was to see if the drug lowers the risk of major heart problems like heart attack, stroke, or death, and improves the heart's pumping functi…

This study tested a new way to help heart failure patients with weak hearts (ejection fraction 35% or less) get the right medications. Over 2,400 patients with implantable defibrillators were included. The approach used a nurse-led algorithm to identify patients and send recommen…

This study looked at two different ways to support heart failure patients after they leave the hospital. One group got a phone call from a care coordinator, while the other could request a home visit from a community paramedic who could connect them with a doctor via video. The g…

This study tested whether a small wearable sensor, combined with a computer model, could detect early signs of worsening heart failure in 176 veterans. Half of the participants were monitored remotely, and their care teams were alerted when the system predicted a flare-up. The go…

This study tested whether doxycycline, an antibiotic, can prevent further heart damage after a heart attack. 174 adults who had a severe heart attack took doxycycline or a placebo twice daily for one week. Three months later, researchers used MRI scans to check heart structure an…

This early-phase study tested whether the heart medication carvedilol could safely prevent heart damage in breast cancer patients receiving chemotherapy with doxorubicin and/or trastuzumab. Researchers assigned 68 women to either usual care or carvedilol based on their risk of he…

This study looked at whether a diabetes drug called empagliflozin, combined with a sleep machine (CPAP), could improve sleep and heart health in 70 adults with both heart failure and obstructive sleep apnea. Participants were randomly assigned to receive the drug or not, and all …

This study tested a mobile app called ENGAGE-HF that helps people with heart failure track their symptoms, vital signs, and weight. The goal was to see if using the app, along with a dashboard for doctors, could improve medication use and quality of life. The study involved 134 a…

This study tested a program called PRADO for people with heart failure after they leave the hospital. The program helps coordinate doctor visits and nursing care for 2 to 6 months. Researchers wanted to see if it reduces hospital readmissions and is cost-effective. The study incl…

This study looked at whether taking a specific probiotic (Lactobacillus plantarum 299v) for 12 weeks could improve exercise ability and blood vessel health in people with chronic heart failure. Ten adults with heart failure participated. The goal was to see if the probiotic could…

This study looked at whether the drug vericiguat can improve blood vessel function, reduce inflammation, and make people with heart failure feel better. 26 adults with heart failure with reduced ejection fraction took vericiguat alongside their standard treatments. Researchers me…

This study tested a device called the DuoCor Ventricular Assist System, an implantable heart pump for people with advanced heart failure. Eight adult patients who needed support for both sides of the heart received the pump. The main goal was to see if patients survived for 3 mon…

This study tested a program to help people with heart disease, stroke, or heart failure in India. The program used health workers, text messages about healthy living, and a computer tool to help doctors. The goal was to see if this approach could improve how well patients follow …

This study tested a web application designed to help people with heart failure optimize their medications. 225 participants used the app for 12 weeks to see if it improved their medication scores. The goal was to make it easier for patients and doctors to follow best-practice tre…

This study tested whether a drug called sacubitril/valsartan works better than enalapril for people with heart failure caused by Chagas disease. About 922 adults with weakened hearts took part. The goal was to see if the new drug could reduce heart-related deaths, hospital stays,…

This study compared two diuretics (water pills), torsemide and furosemide, in about 3,000 adults hospitalized with heart failure. The goal was to see which drug better prevents death or the need for repeat hospital visits over a year. Participants were randomly assigned to one of…

This study tested whether providing pre-made, heart-healthy traditional Navajo meals at home could reduce hospital visits for people with heart failure. Over 200 participants received either these meals or usual care for 60 days. The goal was to see if this approach could lower e…

This study looked at whether a special exercise program is practical and helpful for young cancer survivors (ages 18-45) who have mild heart problems from past treatment. 30 survivors joined the pilot study to test if they could stick with the program and if it improved their hea…

This study tested a program where community health workers visited heart failure patients at home after they left the hospital. The goal was to see if this support helped patients attend follow-up visits and manage their condition. The study included 30 adult heart failure patien…

This early study tested a single injection of HM2002, a circular RNA, given directly into the heart muscle during bypass surgery in 3 people with ischemic heart failure. The main goal was to check safety and tolerability. This is a first-in-human trial, not a cure, and participan…

This study looked at whether a clinic focused on guideline-recommended medications helps heart failure patients. Researchers analyzed data from 342 patients with heart failure and a weak heart pump. They compared patients who went to the special clinic to those who received usual…

This study looked at the safety and effectiveness of taking JARDIANCE® tablets every day for a long time in 1,200 Japanese patients with chronic heart failure. Researchers tracked side effects like low blood sugar, dehydration, and kidney problems, as well as deaths and hospital …

This study looked at the safety of the drug sacubitril/valsartan in Japanese children with heart failure. Eight children who had already finished a previous study took part. The goal was to collect more safety information and give them access to the drug until a child-friendly ve…

This study looked at health records of 1,249 heart failure patients in Portugal to compare two types of medication: sacubitril/valsartan versus older drugs (ACE inhibitors or ARBs). The goal was to see which treatment better prevents death from heart problems or hospital stays du…

This study looked at whether adults with acute illnesses like infections, heart failure, or COPD can be safely treated at home instead of in a hospital. 160 rural patients were randomly assigned to receive hospital-level care at home or usual hospital care. The goal was to see if…

This study looked at whether a daily pill called an SGLT2 inhibitor (dapagliflozin or empagliflozin) can help people without diabetes who had a heart attack and a procedure to open blocked arteries. The goal was to see if the drug lowers the chance of being hospitalized for heart…

This study tested whether a single daily pill containing three proven heart failure medications could help people with a weakened heart pump. The trial involved 212 adults from low-income and racially diverse backgrounds who were not on optimal treatment. The goal was to see if t…

This study tested a procedure called pulmonary artery denervation (PADN) in 30 adults with both heart failure and high blood pressure in the lungs. Participants had already been on standard heart failure medications for at least a month. The goal was to see if PADN could safely i…

This study tested a nurse-led smartphone app to help heart failure patients manage their health after leaving the hospital. 104 patients were split into two groups: one used the app for medication reminders, symptom tracking, and team support, while the other received standard ca…

This study tested whether the drug henagliflozin, given for 6 months after a heart attack, can reduce the size of heart muscle damage and improve heart function. 248 adults who had a specific type of heart attack (STEMI) and underwent a procedure to open blocked arteries particip…

This study looked at whether a dedicated clinic (GDMT Clinic) helps heart failure patients get the right medications compared to usual care. About 300 adults with heart failure, including those with reduced or preserved pumping function, took part. The goal was to see if the clin…

This study looked at whether a procedure called cryoballoon ablation can safely treat atrial fibrillation (an irregular heartbeat) in people who also have severe heart failure. About 1,420 adults with both conditions received the freezing treatment to isolate the veins in the hea…

This study looked at whether a new way of processing heart valves (made from cow tissue) is safe and works well for people who need a new aortic or mitral valve. About 777 adults took part, and researchers checked for valve problems and side effects up to 5 years after surgery. T…

This early-phase study tested a new treatment called CAR-DC in 8 adults with end-stage dilated cardiomyopathy, a condition where the heart becomes enlarged and weak. The therapy uses specially engineered immune cells to target a protein (FAP) found in scar tissue, aiming to reduc…

This study tested two drugs—hydralazine-ISDN and metformin—in 1100 adults with chronic heart failure and reduced heart function. Some participants also had diabetes or were at risk for it. The goal was to see if these drugs could lower the chance of death or hospital stays due to…

This study tested whether probenecid, a drug usually used for gout, can improve heart function and exercise ability in veterans with heart failure. About 99 veterans with reduced heart pumping function took probenecid twice daily for 180 days. The goal was to see if the drug coul…

This study tested whether a team-based program could help doctors prescribe more of the recommended heart failure medications to patients with a weak heart pump. Over 4,300 adults took part. The goal was to increase use of these drugs to reduce deaths and hospital stays.

This study looked at whether a low dose of the cheap, old heart drug digoxin can help people with chronic heart failure. About 982 adults with heart failure and reduced pumping ability took either digoxin or a placebo. The goal was to see if digoxin lowers the chance of heart fai…

This early-stage study tested a new drug called CDR132L in 28 people with stable heart failure caused by reduced blood flow to the heart. The main goal was to check if the drug is safe and how the body processes it. Researchers compared the drug against a placebo to see any side …

This study tested an investigational drug called AZD3427 in 260 adults with heart failure and a related lung condition called pulmonary hypertension (Group 2). The goal was to see if the drug could lower blood pressure in the lungs after 24 weeks of treatment. Participants receiv…

This study tested a device called Barostim NEO in over 1,000 people with advanced heart failure. The device sends mild electrical pulses to a key artery in the neck, which signals the brain to relax blood vessels and reduce strain on the heart. The goal was to see if this therapy…

This study looked at whether the drug sacubitril/valsartan works as well in African American patients with heart failure as it does in others. Over 6,500 African American adults with reduced heart pumping function took part. Researchers measured how many died or were hospitalized…

This study tested two ways to help doctors prescribe the best medications for heart failure patients using remote care. Over 500 adults with heart failure took part, and the goal was to see if these strategies increased the use of recommended drugs. The approach focused on optimi…

This study looked at whether giving heart failure patients healthy meals or fresh produce boxes after a hospital stay can improve their health and reduce emergency visits. 150 adults who were recently hospitalized for heart failure took part. Some received medically tailored meal…

This study looked at whether a specialized clinic run by a heart failure nurse could help patients with heart failure get the right medications after receiving an implantable cardioverter defibrillator (ICD). The goal was to see if this approach improved heart function and reduce…

This study tested whether doing a simple ultrasound at the bedside every day helps doctors better manage fluid levels in patients hospitalized for acute heart failure. The goal was to see if this approach leads to fewer patients being readmitted to the hospital within 30 days. Th…

This study tested a home-based digital health program for 104 adults with heart failure. After leaving the hospital, participants used a smartphone app, cognitive behavioral therapy, and a special monitoring vest to track their heart function. The goal was to see if this approach…

This study looked at whether empagliflozin, a diabetes drug, can improve heart structure in people with heart failure who have normal pumping ability but are not diabetic. Fifty patients took part. Researchers measured heart stress markers like NT-ProBNP and sST2 to see if the dr…

This study looked at 180 adults with heart failure and a leaky mitral valve. Researchers compared taking one drug (ARNI) alone versus taking it together with another drug (SGLT2 inhibitor) to see which better improved heart and valve function. The goal was to find a more effectiv…

This study looked at whether doing cardiac rehabilitation at home, or a mix of home and clinic visits, is as effective as going to the clinic for all sessions. 206 adults with heart conditions like heart attack or heart failure took part. The goal was to see if home-based options…

This pilot study tested whether a simple values-affirmation exercise could help older adults with heart failure stick to their medication routine while in cardiac rehab. 43 participants were randomly assigned to either the affirmation group or usual care. The main goals were to s…

This study looked at 411 people with both heart failure and atrial fibrillation (a fast, irregular heartbeat). It compared two approaches: using a catheter ablation procedure to restore normal heart rhythm, versus simply controlling the heart rate with medication. The goal was to…

This study tested a new way to pace the heart in 150 people with heart failure and a specific type of heart block (left bundle branch block). The goal was to see if directly pacing the heart's natural electrical system (HIS or left bundle branch) works as well as the standard biv…

This study tested a program for people with heart failure that combines remote monitoring (tracking symptoms and weight at home) with nurse education and a hospital check-up. The goal was to see if this approach could reduce hospital stays and deaths. The study included 504 older…

This study tested a new drug called tovinontrine in 557 adults with chronic heart failure and reduced pumping ability. The goal was to see if the drug could safely lower a key heart stress marker (NT-proBNP) compared to a placebo over 12 weeks. Participants had heart failure symp…

This study tested whether a more detailed remote monitoring system could reduce deaths or hospital stays for heart failure patients who have a special heart device (CRT). Over 650 adults were followed for 27 months. The goal was to see if extra monitoring helps catch problems ear…

This study tested a special feature in pacemakers that automatically adjusts timing and pacing to help the heart pump better. 198 people with heart failure and a wide QRS received the device and were followed for 12 months. The goal was to see if the feature improved symptoms, re…

This study tested a remote monitoring system (Seerlinq HeartCore) in 330 adults with chronic heart failure. The system tracked health data and guided treatment changes to prevent worsening symptoms. The goal was to see if this approach could lower the number of hospitalizations a…

This study looked at whether empagliflozin, a medicine already used for diabetes and heart conditions, can help improve the heart's shape and pumping ability in people with diabetes who had a major heart attack. Two hundred patients took either a 10 mg or 25 mg dose and were moni…

This study looked at whether closer collaboration between doctors and pharmacists could reduce the number of heart failure patients who need to be readmitted to the hospital within three months. Researchers compared standard care to a more coordinated approach involving pharmacis…

This study tested a technology-based program that involves family members to help people with advanced heart failure take better care of themselves after leaving the hospital. The program used a smartphone app to support self-care and improve quality of life. 270 patients in Hong…

This study tested whether a smartwatch can pick up signs of heart failure by tracking body signals like heart rate and movement, and recording voice patterns. Researchers compared 56 people with and without heart failure during physical tasks and daily life. The goal is to find n…

This study checked how well a new blood test (called BNP) works for diagnosing heart failure. Researchers tested samples from 1361 people to see if the test correctly identifies those with heart failure. The goal was to make sure the test gives accurate results on a new machine.

This study tested a new wearable device called Seerlinq HeartCore that uses light sensors to measure pressure inside the heart without needles or surgery. 131 adults with heart failure took part to see if the device could accurately track changes in heart pressure and help doctor…

This study tested a new way to screen for heart failure in people aged 65 and older during regular checkups with their general doctor. Researchers used a simple questionnaire, a blood test, and a heart ultrasound to find undiagnosed cases. The goal was to see if this approach cou…

This study tested whether measuring a blood marker called ST2 can improve the diagnosis and management of heart failure patients. Researchers followed 123 hospitalized adults to see if ST2 levels could help predict and reduce the chance of being readmitted within one month. The g…

This study tested a new blood test called HEARTBiT that may detect when the body is rejecting a transplanted heart. Currently, patients need many invasive heart biopsies to check for rejection. The test looks at 9 RNA markers in the blood and could be faster, cheaper, and less pa…

This study tested a special ultrasound technique called ShearWave Elastography to measure liver stiffness as a way to assess liver disease without a needle biopsy. Over 1,200 adults with chronic liver disease, liver transplants, or heart failure had a quick scan during their regu…

This study aimed to create better diagnostic tools for heart failure with preserved ejection fraction (HFpEF), a type of heart failure that is difficult to diagnose, especially in older adults with conditions like high blood pressure or obesity. Researchers tested a combination o…

This study looked at whether a diet low in salt and rich in fruits, vegetables, and whole grains (the DASH diet) could prevent heart failure in 71 Veterans with high blood pressure and metabolic syndrome. Participants followed the diet and were monitored for changes in artery sti…

This study tested whether nebivolol, a beta-blocker, could prevent heart problems in 51 boys aged 10–15 with Duchenne muscular dystrophy. Participants had healthy hearts at the start and were randomly given either the drug or a placebo. The goal was to see if the drug could stop …

This study tested if a 12-week home-based walking program could help people with heart failure feel less depressed, less frail, and have a better quality of life. 68 adults hospitalized for heart failure were split into two groups: one got standard health education, and the other…

This study looked at whether providing medically tailored meals for 12 weeks could improve the diet quality of people with heart failure. Sixty participants from California took part. The main goal was to measure changes in their eating habits using a standard healthy eating scor…

This study tested whether watching animated nutrition education videos could help people with heart failure improve their eating habits, reduce symptoms, and feel better overall. 70 adults aged 45-60 with moderate heart failure were split into two groups: one watched the videos, …

This study tested two methods of pacing the left side of the heart in people with severe heart failure. The standard method paces from outside the heart, while the new method paces from inside. The goal was to see if the new method improves heart function more and helps more pati…

This study tested whether drinking a ketone supplement could improve heart function in 20 people with heart failure. Participants had MRI scans after taking the ketone drink or a sugar placebo. The goal was to see if the drink helped the heart pump more blood.

This study tested whether heart failure patients could leave the hospital earlier by receiving a special furosemide injection at home instead of staying in the hospital for IV treatment. 172 adults with heart failure took part. The goal was to see if this approach increased the n…

This study tested a web-based program called "Heart to Heart" that helps heart failure patients, their family caregivers, and nurses work together better. 150 adults with heart failure, their caregivers, and nurses used the program to improve communication and care. The goal was …

This study tested a 12-week program for heart failure patients and their family caregivers. The program focused on improving their relationship, emotional strength, and quality of life. 192 patient-caregiver pairs took part. The goal was to see if this support program could reduc…

This study tested a program for caregivers of people with advanced heart failure. The program helped caregivers build on their strengths, find purpose, and set goals for a healthier lifestyle. Researchers wanted to see if it could improve caregivers' quality of life and reduce th…

This study tested whether heart failure patients can do cardiac rehabilitation at home using a tablet app instead of going to the hospital. Thirty stable patients were split into two groups: one did rehab at home with remote monitoring, the other at the hospital. The goal was to …

This study tested whether a new extended-release version of the diuretic torsemide helps people with heart failure get rid of more salt (sodium) in their urine after lunch compared to the standard immediate-release version. Twenty adults with stable heart failure who were already…

This study looked at whether the sequence of different exercises during a single session can improve heart function in men with chronic heart failure. Sixty men aged 55-65 with class II or III heart failure took part. Researchers measured heart pumping ability and quality of life…

This study looked at whether a cardiac rehab program with two types of aerobic exercise could help heart failure patients who also have muscle loss (sarcopenia). 22 patients aged 18-75 with moderate heart failure took part. The goal was to see if exercise could improve their brea…

This study looked at whether special lymphatic exercises can reduce fluid overload symptoms like shortness of breath, leg swelling, and fatigue in people with heart failure. 80 participants were split into two groups: one did lymphatic exercises plus daily monitoring, the other o…

This study tested a 12-week online program that combines gentle movement, breathing exercises, and coping skills for adults with chronic conditions like heart failure, liver disease, or cancer. The goal was to see if it could reduce anxiety and depression. Over 800 people took pa…

This study tested whether a slow-release version of the water pill torsemide works better than the standard version at reducing urgent, frequent urination in people with chronic heart failure. 24 adults aged 50 and older with both conditions took each version for four weeks. The …

This study tested a sleep improvement program delivered through WhatsApp for people with heart failure. 28 participants received personalized sleep tips and reminders based on their readiness to change. The goal was to see if this simple, phone-based approach could improve sleep …

This study looked at whether a personalized exercise program can improve fitness and well-being in people with dilated cardiomyopathy, a type of heart muscle disease. 300 participants wore an Apple Watch to track activity and symptoms over 13 months. The main goal was to see if m…

This study tested whether a structured plan for giving diuretics (water pills) to patients hospitalized with worsening chronic heart failure is safer and more effective than usual care. About 299 adults took part. The goal was to see if the protocol could better manage fluid buil…

This study tested whether high-intensity interval training (short bursts of hard exercise) is better than moderate continuous training (steady, moderate exercise) for improving nerve, blood vessel, and muscle function in 35 adults with heart failure. Participants had mild to mode…

This study tested a program that helps seriously ill heart failure patients receive specialized care at home instead of in the hospital. Doctors were encouraged to refer eligible patients to a home-based palliative care service. The goal was to see if this approach reduces hospit…

This early-stage study tested a new patch that delivers the drug furosemide under the skin to help remove excess fluid in people with heart failure. Twenty hospitalized adults received a single dose to see if the patch is safe and works well. The goal is to offer a simpler altern…

This study tested a 6-month program called ENABLE for heart failure patients and their caregivers in Singapore. The program provides education, support, and advice to improve quality of life. Researchers enrolled 125 participants to see if the program was feasible and acceptable.…

This study looked at how HeartInsight, a monitoring tool in implanted heart devices, alerts doctors to worsening heart failure. About 100 patients with heart failure and a special CRT-D device took part. The goal was to see how doctors use these alerts in everyday care to manage …

This study looked at how heart devices and treatments affect a blood protein called von Willebrand factor, which helps blood clot. Researchers studied 500 adults with advanced heart failure or aortic stenosis to understand when and why bleeding problems happen. The goal was to le…

This study looked at over 30,000 adults admitted to hospitals in Maryland to understand why some patients wait in the emergency room even after being admitted (called boarding). Researchers wanted to find out which patients are more likely to board, how boarding increases healthc…

This completed study looked at whether an AI-enhanced electrocardiogram (ECG) can predict heart damage caused by cancer treatments like chemotherapy and immunotherapy. Researchers analyzed data from over 31,000 adults who had an ECG before starting cancer therapy. The goal was to…

This study tested whether an augmented reality tool (a phone app that shows 3D images) could help heart patients understand their discharge instructions better than the usual paper report. About 300 adults with heart conditions like heart attack or heart failure took part. The go…

This study used advanced MRI scans to look at the hearts of 276 people with chronic kidney disease, including those on dialysis. The goal was to understand why heart problems are so common in kidney patients and to find better ways to predict and manage these risks. Researchers f…

This study looked at whether people with chronic heart failure can complete a 12-week exercise program at home after a hospital stay. 30 patients were enrolled. Researchers measured how many finished the program and tracked quality of life and exercise ability. The goal was to se…

This study tested whether a mobile app that gives visual feedback and motivational reminders can help older adults (60+) with conditions like COPD, heart failure, or Parkinson's spend more time out of bed while in the hospital and for three months after going home. Researchers tr…

This study tested whether an Apple Watch can reliably measure key health indicators like oxygen use during exercise in people with heart conditions. Researchers compared smartwatch data to standard medical equipment in 50 adults with heart disease or in athletes. The goal was to …

This study looked at 18 heart failure patients with a specific electrical issue called left bundle branch block. Researchers mapped where to place a pacemaker lead to better coordinate heartbeats. The goal was to understand the best pacing spots and see if this approach improves …

This study looked at how well different heart pressure tests work. Researchers compared non-invasive ultrasound (echocardiography) with invasive catheter measurements in 623 adults. The goal was to see which tests best detect high pressure in the heart's main chamber, a key sign …

This study looked at 502 people with heart failure who were getting an implantable defibrillator (ICD) to prevent sudden cardiac arrest. Researchers used a special MRI to see if scarring in the heart could predict who would later need a shock from their device. The goal was to le…

This study watched 49 adults with acute heart failure to see how their bodies get rid of extra fluid during a hospital stay. Researchers used exams, blood tests, and ultrasound to track the process. Patients were followed for one year to see who needed to return to the hospital o…

This completed study surveyed 608 heart and kidney doctors to understand their awareness and use of a blood test called hsCRP, which measures inflammation. The goal was to learn what doctors think about using this test to identify inflammation in patients with heart disease, kidn…

This study tested a program to improve heart failure care for Black and Latinx patients who are often treated on general medicine instead of cardiology. The program included standard treatment plans, cardiology checkups, and help with transportation. Researchers tracked whether m…

This study looked at how aerobic exercise changes the activity of genes in heart cells of people with heart failure. Forty adults with stable heart failure were split into two groups: one received standard medication, and the other added 36 sessions of high-intensity interval tra…

This study checked if special heart devices (pacemakers and defibrillators) are safe during strong 3.0 Tesla MRI scans. 64 adults with these devices received an MRI and were followed for one month. The goal was to see if any serious problems happened because of the scan. The resu…

This study tested an internet-based support program for 202 caregivers of people with heart failure. The program was designed to help caregivers feel more prepared and supported in their role. Researchers measured changes in preparedness, competence, and rewards of caregiving aft…

This study tested whether artificial intelligence (AI) could predict a person's risk of developing a specific type of heart failure (HFrEF) up to five years in advance, using only a standard ECG. Researchers analyzed data from over 286,000 adults in China and the United States. T…

This study collected information from 383 patients across global heart centers to understand how a newer pacing method called conduction system pacing (CSP) works in everyday practice. The goal was to learn about the benefits and risks of CSP for people with slow heartbeats or he…

This study involved 1,249 heart failure patients at Stanford to see if regularly collecting a short quality-of-life survey during clinic visits improves health outcomes and treatment decisions. Half the patients started the survey right away, while the other half began a year lat…

This study looked at whether using a heart ultrasound during pacemaker implantation helps doctors place the wires more accurately, reduces procedure time, and cuts down on X-ray use. 33 people with heart failure who needed a pacemaker took part. Researchers compared results to st…

This study looked at two methods for assigning care coordinators to older adults (65+) who have heart disease or related risks like diabetes or high blood pressure. The goal was to see which method better prevents emergency room visits and hospital stays. Researchers compared ass…

This study looked at whether orienteering (a navigational walk) is as good as regular walking for heart rehab. 40 people with heart disease completed both types of walking sessions. Researchers measured heart rate and how much patients enjoyed each activity. The goal was to see i…

This study tested whether sending official digital letters to heart failure patients could help them start a new medicine (SGLT-2 inhibitors) faster. About 6,000 adults in Denmark with heart failure were invited to check if they were eligible. The goal was to see if this digital …

This study looked at past patient records to see if a computer program could predict who would need to be readmitted to the hospital within 30 days of leaving. Researchers used data from 372 patients treated at home through a hospital program. The goal was to improve care, not to…

This study looked at 58 adults with heart failure to find out why they return to the emergency room within 30 days of being discharged. Researchers reviewed medical records and follow-up visits to identify key factors. The goal is to improve care and reduce repeat hospital visits…

This study tested a new way to give the water pill furosemide—as a single shot under the skin—compared to the standard method through an IV line. Twenty-one healthy adults aged 45 to 80 took part. The goal was to see how well the body absorbs the drug and how it affects urine out…

This study translated the Minnesota Living with Heart Failure Questionnaire into Urdu and tested it with 210 heart failure patients in Pakistan. The goal was to ensure the Urdu version is accurate and reliable for measuring quality of life. This helps doctors better understand an…

This study examined how COVID-19 lockdowns impacted over 1,300 people with chronic conditions like heart disease, multiple sclerosis, and hemophilia. Researchers looked at changes in medication use, lifestyle habits, and stress levels. The goal was to understand the health risks …

This study reviewed the medical records of over 13,000 adults with chronic heart failure enrolled in a French remote monitoring program between 2021 and 2024. Researchers wanted to see how often doctors prescribed a type of medication called SGLT2 inhibitors, and whether factors …

This study looked at how people with heart failure feel over time, using surveys and interviews. Researchers also collected blood samples from some participants to find biological clues that might affect quality of life. The goal was to better understand when and why heart failur…

This study tested new MRI methods to better detect bleeding inside the heart muscle after a heart attack. Researchers studied 14 adults who had a heart attack to see if these scans could map the bleeding more clearly than standard MRI. The goal is to help doctors identify patient…

This study looked at medical records of 4,000 heart failure patients to see if combining routine blood tests (like NT-proBNP) with heart scan results (like fat density around the heart) could better predict who might die within a year. The goal is to improve personalized risk ass…

This study tested whether sending a reminder to a patient's primary doctor could help find hidden heart failure. The researchers looked at 115 patients with high BNP levels (a sign of possible heart strain) but no recent heart imaging. The goal was to see if the alert would lead …

This study tested an automatic alert in electronic health records to remind doctors to prescribe recommended heart failure medications. Over 1,100 patients with heart failure and reduced pumping function took part across four health systems. The goal was to see if the alert incre…

This study tested whether motion-capture tools can objectively measure physical limitations in elderly people with heart failure. Researchers analyzed movements during simple tasks using wearable sensors and cameras. The goal was to develop a new way to classify patients by their…

This study looked at how increasing ketone levels in the blood affects heart function in 41 adults with type 2 diabetes and heart failure. Researchers used heart scans to measure how well the heart pumps blood and how it uses sugar for energy. The goal was to understand the body'…

This study tested whether a program combining nurse coaching calls and home monitoring of vital signs is practical and acceptable for older adults with heart failure. 46 patients participated after a hospital stay. Researchers measured how many people joined, stuck with the progr…

This study tested whether a newer, more compact camera (CZT) works as well as a standard camera for taking pictures of heart nerve activity in people with heart failure. 45 adults with stable heart failure received a special tracer injection to highlight nerve function. The goal …

This study tested whether cardiac MRI can replace some risky procedures for children with heart failure or heart transplants. Researchers used MRI to guide heart catheterization and biopsies, aiming to reduce radiation exposure and improve accuracy. The study involved 113 childre…

This early-stage study tested a single dose of an investigational drug called THRV-1268 in 16 healthy obese adults. The main goal was to check if the drug is safe and how well the body handles it, not to treat any disease. Researchers also measured how the drug moves through the …

This study looked at whether common heart failure drugs are linked to falls in people aged 65 and older. Researchers analyzed a global safety database of 100,000 reports to find patterns. The goal was to identify which medications might raise fall risk, not to test a new treatmen…

This study gathered information from 254 Mexican adults with heart failure and reduced pumping ability. Researchers looked at their medical treatments, health outcomes, and any obstacles to receiving proper care. The goal was to better understand how heart failure is managed in r…

This study looked at data from 526 patients treated at home through a hospital-at-home program. Researchers used a computer algorithm to try to predict if a patient would get worse during their stay. The goal was to see if machine learning could help doctors spot problems earlier…

This study observed 257 adults with heart failure who were prescribed dapagliflozin as part of their routine care. Researchers tracked how long patients stayed on the medication, any changes in treatment, and how their quality of life changed over time. The goal was to gather rea…

This study looked at data from over 2,400 heart failure patients to find better ways to treat them. Researchers tested a care model that sorts patients by risk to improve survival and reduce hospital visits. The goal was to see if adding new health measures could help predict out…

This study tested how easy and acceptable the P-STEP mobile app is for people with chronic conditions like asthma, COPD, heart disease, or type 2 diabetes. 178 adults in Leicester, UK, used the app for 12 weeks and gave feedback on its usability. The goal was to see if the app is…

This study tested whether gentle reminders sent to doctors could increase prescriptions of two types of heart failure medications that can save lives and prevent hospital stays. Researchers worked with 81 primary care and heart doctors at a VA hospital. The goal was to see if the…

This study looked at whether signs of heart failure can be found in fluid just under the skin, instead of in blood. Twenty heart failure patients had their skin fluid tested using a special device during exercise. The goal was to see if this method could help predict when the dis…

This study looked at 158 heart failure patients aged 18-65 in Taiwan to understand how their health literacy and stress levels relate to their quality of life. Researchers used questionnaires and machine learning to find patterns. The goal was to help nurses better assess and sup…

This study examined how well hospitals in Germany follow recommended treatments for heart failure with reduced ejection fraction (HFrEF) after a patient's condition worsens. Researchers looked at 899 patients across different types of heart failure centers and non-specialized cen…

This study tested whether a portable ultrasound device can accurately measure muscle loss in people with heart failure, compared to the standard X-ray method. Researchers enrolled 48 participants, including healthy volunteers and heart failure patients. The goal was to see if ult…

This study looked at how beta-blocker medicines improve heart function in people with heart failure. Researchers measured changes in the heart's ability to contract and pump blood. The goal was to understand the underlying mechanisms, not to test a new treatment. 55 adults with n…

This study looked at ways to protect the right side of the heart after patients receive a mechanical pump (LVAD) for heart failure. Twenty adults who had LVAD surgery were monitored closely for several days. The goal was to find better methods to prevent right heart problems afte…

This study looked at 32 adults who had heart surgery to see if a liver ultrasound could help find right-sided heart problems. Right heart issues are common after surgery and can lead to kidney or liver failure. The researchers measured blood flow in the liver and compared it to s…

This study looked at 30 children with heart failure to understand how their breathing and sleep are affected. Researchers measured the effort it takes for these children to breathe and checked their sleep quality. They also tested whether using a breathing mask (CPAP) while awake…

This study tested a device that measures foot volume changes in people with heart failure. The goal was to see if it helps doctors adjust diuretic (water pill) treatment at home and detect early signs of fluid buildup before a hospital visit. 23 patients participated, and the stu…

This study tested whether a 'teach-back' education session—where patients repeat discharge instructions in their own words—helps heart failure patients better manage their condition at home. Researchers enrolled 57 adults hospitalized with heart failure and measured changes in se…

This study looked at whether watching videos or reading text helps people with heart failure learn more about their condition. 130 adults with heart failure took part. They were randomly assigned to watch videos or read text about heart failure medications and self-care, and then…

This study involved 100 patients with serious illnesses like cancer, heart failure, COPD, or ALS who were receiving palliative care. Researchers used a questionnaire to find out patients' spiritual needs and then provided specialized spiritual care to address them. The goal was t…

This study looked at how the heart failure drug Entresto lowers blood pressure. Researchers tested 46 people with heart failure to see if a nausea drug called aprepitant changes how Entresto works. The goal was to understand the body's response, not to test a new treatment.