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Could a common gout pill help Veterans' failing hearts?

NCT ID NCT04551222

First seen Nov 10, 2025 · Last updated Jun 18, 2026 · Updated 29 times

Summary

This study tested whether probenecid, a medicine usually used for gout, can improve heart function and exercise ability in veterans with heart failure. About 99 veterans with a specific type of heart failure took probenecid twice daily for 180 days. Researchers measured changes in heart function using ultrasound and exercise tests to see if the drug helps manage the condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cincinnati VA Medical Center, Cincinnati, OH

    Cincinnati, Ohio, 45220-2213, United States

  • Hunter Holmes McGuire VA Medical Center, Richmond, VA

    Richmond, Virginia, 23249-0001, United States

  • Louis Stokes VA Medical Center, Cleveland, OH

    Cleveland, Ohio, 44106-1702, United States

  • Providence VA Medical Center, Providence, RI

    Providence, Rhode Island, 02908-4734, United States

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

    Boston, Massachusetts, 02130-4817, United States

Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.