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Heart failure mystery: can tracking fluid congestion predict readmission?

NCT ID NCT06244693

Knowledge-focused Sponsor: University of Chile Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study observed 49 adults hospitalized with acute heart failure to learn how fluid congestion behaves during treatment. Researchers tracked clinical signs, lab tests, and ultrasound measures, then followed patients for a year to see who was readmitted or died. The goal is to better understand the decongestion process and identify factors that predict poor outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand how to manage fluid buildup in heart failure patients, potentially reducing hospital readmissions.
What could go wrong
This is a small, completed observational study with only 49 participants, so findings may not apply to all heart failure patients and won't directly lead to a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

49 people

The number who actually took part.

Started

Apr 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with heart failure aged 18 years or above that are admitted in emergency room or outpatient clinic for acute decompensation of new or known heart failure, excluding diagnostics that mimics heart failure. Everyone has to be discharge from Hospital Clínico Universidad de Chile.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults diagnosed with decompensated heart failure in the emergency department or cardiology outpatient clinic at the Clinical Hospital of the University of Chile (HCUCh). * Profile of warm-wet and cold-wet type heart failure. * Spontaneous ventilation with or without non-invasive mechanical support. * Desire for participation validated through informed consent. Exclusion Criteria: * Dry-type heart failure profile (warm and cold) * Diagnostics that mimics heart failure (valvular heart disease, cardiomyopathies, and others diagnostic different from heart failure). * Septic, distributive, or obstructive shock * Polytraumatized * Severe burns * Invasive mechanical ventilation * Permanent renal replacement therapy * Severe dependence * Presence of terminal illness with a prognosis of survival less than one year * Presence of traumatic conditions that prevent the use of thoracic ultrasound, such as a flail chest or moderate to severe burn on the left hemithorax. * Lack of a support network or contact. * Cardiorespiratory arrest * Refusal to participate as indicated in the informed consent. * Presence of psychological or intellectual disability that prevents expressing the will to participate.

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Congestion Heart failure

Contacts and locations

Locations

  • Departamento Cardiovascular - Hospital Clínico Universidad de Chile

    Santiago, Metropolitan, 8380456, Chile

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