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Simple exercises may ease fluid overload in heart failure

NCT ID NCT05834400

Symptom relief Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether a set of lymphatic exercises could reduce fluid overload symptoms like shortness of breath, leg swelling, and fatigue in people with heart failure. Eighty participants were randomly assigned to either do the exercises twice daily for four weeks or just monitor their symptoms. Researchers compared changes in symptoms, fluid levels, sleep, and quality of life between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lymphatic exercise training
What this could lead to
If it works, this could offer a simple, drug-free way to reduce fluid buildup and improve quality of life for people with heart failure.
What could go wrong
This is a small pilot study with only 80 participants, so results may not apply to everyone. The exercises require daily commitment, and benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Aug 2023

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical diagnosis of HF with New York Heart Association (NYHA) functional class II, III, or IV * Willing and able to complete the home-based TOLF program upon discharge from the hospital to home Exclusion Criteria: * Severe liver or kidney insufficiency or malignant tumors * A terminal condition with a life expectancy of \< 6 months * Received or waiting for heart transplantation * Pregnancy * Cognitive impairment (e.g., dementia) * Severe psychiatric condition (psychotic disorder, severe depression, suicidal intent) * Inability to converse in English

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Conditions

The condition(s) this trial relates to.

Edema, Cardiac heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure

Contacts and locations

Locations

  • Cooper University Health Care (Cooper)

    Camden, New Jersey, 08103, United States

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