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New MRI technique spots hidden heart bleeding

NCT ID NCT03531151

Knowledge-focused Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested new MRI methods to detect bleeding inside the heart muscle after a heart attack. Researchers studied 14 patients to see if these scans could better identify damage that raises the risk of heart failure. The goal was to improve imaging, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better MRI techniques for identifying patients at high risk of heart failure after a heart attack.
What could go wrong
This was a very small, observational study (14 people) focused on imaging methods, not a treatment trial. The results may not directly change patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

14 people

The number who actually took part.

Started

Apr 2018

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population specific to this project are ST-elevated myocardial infarction (STEMI) patients being treated with reperfusion therapy.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Between the ages of 18 and 80 * Patients must be able to read and understand English * Participants must sign the informed consent form * Elevated and delayed peak creatine kinase-MB and troponin I (cTnI) and troponin T (cTnT) in blood serum, * ST elevation detected on ECG Exclusion Criteria: * contraindications to cardiac MRI, including claustrophobia * advanced renal disease (estimated glomerular filtration rate 30 mL/min) or hypersensitivity to gadolinium * presence of a cardiac pacemaker or implanted cardiac cardioverter defibrillator * pregnancy * personal or family history of hypertrophic cardiomyopathy * inability to provide informed consent * history of seizure disorder

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Conditions

The condition(s) this trial relates to.

cardiomyopathy endomyocardial fibrosis heart failure Hemorrhage ischemia reperfusion injury myocardial infarction myocardial ischemia Myocardial Reperfusion Injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure Hemorrhage Ischemic cardiomyopathy Ischemic heart disease Myocardial edema Myocardial fibrosis Myocardial infarction Myocardial injury Myocardial ischemia Myocardial necrosis Myocardial reperfusion injury

Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

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