Myocardial injury

This study looks at whether doing hip fracture surgery within 6 hours, instead of waiting longer, can reduce deaths in patients who also have a recent heart injury. About 1100 adults aged 45 and older with a hip fracture and elevated troponin (a sign of heart damage) will be rand…

This trial tests whether eplerenone, a drug used for high blood pressure and heart failure, can help people who have had a heart attack or heart injury but no blocked arteries. Many of these patients have damage to tiny blood vessels in the heart. The study will involve 400 adult…

This study tests whether ciprofol, a newer sedative, can reduce heart injury after lung surgery compared to the standard drug propofol. About 1,058 adults aged 45–80 having video-assisted lung surgery will be randomly assigned to receive one of the two drugs during anesthesia. Th…

This study is testing a new way to analyze blood samples to see if it can better tell when someone is having a heart attack. Current tests can be misleading in patients with other conditions like kidney failure. Researchers will look at how troponin T, a protein released during h…

This study tests whether a single injection of a GLP-1 drug (dulaglutide), given 1 to 14 days before planned non-cardiac surgery, can reduce heart muscle injury in 372 adults at risk. Participants are randomly assigned to receive the drug or standard care. The goal is to see if t…

Researchers are studying whether an ischemic stroke in the middle cerebral artery territory triggers inflammation and scarring in the heart muscle. The trial enrolls 44 adults with acute stroke and 24 people with stroke-like symptoms but no brain infarct as a comparison group. Pa…

This study aims to understand why fatty plaques in heart arteries suddenly rupture, causing heart attacks, and why some people experience more heart muscle damage than others. Researchers will use advanced imaging, blood tests, and genetic analysis in about 2,000 patients undergo…