Heart attack test gets a Tune-Up: new method aims to cut false positives
NCT ID NCT04465591
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new way to analyze blood samples to see if it can better tell when someone is having a heart attack. Current tests can be misleading in patients with other conditions like kidney failure. Researchers will look at how troponin T, a protein released during heart injury, breaks down into fragments. The goal is to see if the fragmentation pattern can help doctors make a more accurate diagnosis. The study will enroll 1,500 participants.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- troponin T fragmentation test (blood test)
- What this could lead to
- If successful, this test could help doctors more accurately diagnose heart attacks and avoid false alarms from other conditions like kidney disease.
- What could go wrong
- This is an early observational study, so the test may not prove reliable enough for routine use. It is not a treatment and will not directly improve patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2020
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients are prospectively recruited from the Heart Center, Department of Medicine and Kidney Center of the study hospital. All patients aged 18 years are eligible.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Troponin T fragmentation sample collected from a recruited patient. Exclusion Criteria: * Age \<18
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Turku University Hospital, Heart Center
RECRUITINGTurku, Southwest Finland, 20521, Finland
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University Hospital Zurich
ENROLLING_BY_INVITATIONZurich, 8091 Zurich, Switzerland
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Other studies related to the condition(s) this trial covers.
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