MYOCARDIAL ISCHEMIA

This study tests a new type of heart stent that slowly dissolves over time. It is designed for people with long blockages in their coronary arteries. The goal is to see if the stent is safe and works well to keep arteries open and reduce heart problems over one year. About 100 pa…

This study tests whether using just one blood thinner (single antiplatelet therapy) is safer and as effective as two blood thinners (dual antiplatelet therapy) in older adults or those at high risk of bleeding who have had a heart procedure with a drug-coated balloon. About 576 p…

This study is checking how well two new stents (Synergy XD and Synergy Megatron) work in everyday medical practice for people with coronary artery disease. About 2000 adults getting these stents will be followed to see if they have fewer heart attacks, need repeat procedures, or …

This study compares two imaging methods for guiding treatment of hardened coronary arteries. About 700 adults with heart disease will either receive CT-guided or standard ultrasound-guided care during stent placement. The goal is to see if the CT approach improves stent expansion…

This study is testing a drug called regadenoson in children who need a heart stress test. The drug helps doctors see how well blood flows to the heart. The goal is to check the drug's safety and how the body processes it in different age groups, from infants to teenagers.

This study tests a new type of heart stent made from magnesium that slowly dissolves over time, compared to a permanent metal stent. The goal is to see if the dissolvable stent is safe and works as well for people with blocked heart arteries. About 1,859 adults with coronary arte…

This study aims to improve how doctors diagnose a rare heart condition where a coronary artery grows from the wrong spot, which can cause sudden cardiac death in young athletes. Researchers will use artificial intelligence and 3D computer models to analyze CT scans and predict wh…

This study tests a new computer program that helps doctors diagnose blocked heart arteries from CT scans more accurately. Researchers will look at past scans from 1,000 patients to see if the software can reduce the need for invasive tests like angiograms. The goal is to make dia…

This study is testing whether a new smartphone-based 12-lead ECG device can accurately diagnose heart attacks (STEMI and NSTEMI) compared to standard hospital ECG machines. About 1,000 adults with chest pain will be enrolled in emergency departments. The goal is to see if the por…

This study looks at 570 people with chronic coronary syndrome (ongoing heart artery disease causing chest pain). It compares two approaches: immediate heart catheterization plus medication optimization versus medication alone. The goal is to see which strategy better relieves ang…

This study tests whether adding special breathing muscle exercises to a standard cardiac rehab program helps people with narrowed heart arteries recover better. About 72 adults who had a heart procedure will participate. The goal is to see if this extra training improves exercise…

This early study tests a new device called the A-FLUX Reducer for people with chest pain caused by small heart vessel disease (microvascular dysfunction). The device is placed in a vein near the heart to improve blood flow and reduce symptoms. About 30 adults with persistent ches…

This study is testing whether artificial intelligence can make CT scans of the heart better at predicting future heart attacks. Researchers will follow 10,000 adults who are already getting a heart CT for medical reasons. Participants will also give blood samples, have an ECG, an…

This study is looking at whether people with psoriasis have a higher risk of heart disease. Researchers will follow 1,000 adults with psoriasis, using heart scans and blood tests to find early warning signs. The goal is to better understand the link between psoriasis and heart pr…

This study looks at whether a sensitive blood test can find heart damage in adults having leg surgery with a nerve block. Researchers will measure troponin levels during and after surgery in 54 participants. The goal is to see if this test helps predict heart problems, not to tre…

This study looks at how minimally invasive lung cancer surgery affects the heart's electrical activity. Researchers will monitor 100 adult patients before, during, and after surgery to see if temporary changes occur. The goal is to better understand heart stress from this procedu…