Rutgers, The State University Of New Jersey

This study is testing whether two different exercise programs—cardio-dance fitness versus strength, flexibility, and balance training—can improve brain health and reduce Alzheimer's disease risk in older African Americans. Researchers will enroll 280 sedentary adults aged 60+ to …

This study is testing whether adding cholesterol-lowering statin drugs can protect the heart in patients receiving targeted therapy for early-stage HER2-positive breast cancer. Researchers want to see if statins reduce treatment delays or early stops caused by heart side effects.…

This study is testing whether taking just one long-acting insulin shot per day works as well as taking that shot plus three additional short-acting shots with meals for controlling diabetes during pregnancy. Researchers want to see if the simpler one-shot approach controls blood …

This study is testing if the weight loss medication tirzepatide can help people with early-stage, hormone-positive breast cancer lose weight and potentially improve their long-term outcomes. It will involve 40 participants who have finished their main cancer treatment but are ove…

This study is testing whether liver transplantation can help people with advanced bile duct cancer that can't be surgically removed. Patients first receive chemotherapy to control their cancer for at least 6 months, then receive a liver transplant if they remain eligible. The goa…

This study is testing a combination of chemotherapy drugs (called sFOLFOXIRI) for people with advanced stomach or esophageal cancer that has spread and cannot be removed by surgery. The main goal is to see how well this treatment shrinks tumors and controls the cancer's growth. R…

This study is testing if a more intensive form of therapy for PTSD (Post-Traumatic Stress Disorder) works better for people who are also in treatment for substance use problems. It compares a condensed schedule of therapy sessions to the usual care. The goal is to see if this app…

This study is testing a new combination of four cancer drugs for people with advanced colorectal cancer that has continued to grow despite previous treatments. The goal is to see if this alternating drug schedule can stop or slow the cancer's progression. About 50 participants wi…

This study is testing whether updating radiation treatment plans at set times during therapy can reduce damage to healthy heart and lung tissue in people with non-small cell lung cancer. Researchers want to see if this adaptive approach lowers side effects like lung inflammation …

This study aims to make a common chemotherapy treatment safer by using a genetic test. It will check if adjusting the drug dose based on a patient's specific gene (DPYD) reduces severe side effects compared to the standard dose. The trial includes 100 adults with cancers like col…

This study is developing and testing a smartphone app designed to help pregnant women in Nepal manage gestational diabetes. The app provides support for tracking diet, activity, and blood sugar, aiming to improve health outcomes for both mother and baby. Researchers will compare …

This study is testing if starting people on a higher dose of the addiction medication buprenorphine in the emergency room is safe and helps more people get into follow-up treatment. It focuses on people with opioid addiction who test positive for fentanyl. The goal is to see if a…

This study is testing if a simple text message program can help emergency room patients with diabetes. The texts provide educational materials and connect people to helpful resources. Researchers want to see if this support improves patients' knowledge, reduces their stress about…

This study is testing a new smartphone app designed to help cancer survivors quit smoking. The app delivers mindfulness-based support in real-time, combined with brief counseling and nicotine replacement therapy. Researchers are recruiting 50 adult cancer survivors who currently …

This study is testing if adding a drug called tislelizumab after radiation or other local treatments helps people with liver cancer that cannot be surgically removed. The goal is to see if this combination treatment can keep the cancer from growing or spreading for a longer perio…

This study compares two wound dressings used after surgery for hidradenitis suppurativa, a painful skin condition. Researchers want to see if a newer dressing with silver and a pain reliever helps patients heal faster, with less pain and fewer infections, compared to the standard…

This study is testing a digital tool called mySmartSkin, designed to help people who have had melanoma perform more thorough skin self-exams. Researchers will compare the app's effectiveness against a basic educational webpage to see if it leads to better exam habits and earlier …

This study is testing a telehealth coaching program designed specifically for Hispanic adults at high risk for lung cancer. Bilingual patient navigators help participants understand and decide about getting a low-dose CT scan for early cancer detection. The research aims to see i…

This study is testing whether melatonin, a common over-the-counter supplement, can prevent kidney damage in hospitalized patients who need strong antibiotics. It will involve 300 adults who are prescribed a specific combination of antibiotics. Participants will receive either mel…

This study is testing whether playing a specific online brain training game can help maintain thinking skills in healthy older adults. Researchers want to see if practicing multitasking in the game improves daily mental abilities and could potentially help reduce the risk of futu…

This study is testing if a medication called sulfasalazine can help prevent pregnant women from having another preterm birth. It will involve 50 women with a history of early delivery. Researchers will check if the drug lowers a specific hormone in the blood and if it actually re…

This study is developing and testing a mobile health program delivered through WhatsApp to help Hispanic adults reduce their risk of skin cancer. The program aims to teach sun protection habits like using sunscreen and wearing hats, and to encourage regular skin self-exams. Resea…

This study is testing whether a telehealth coaching program helps patients and their doctors make better, more informed decisions about lung cancer screening. It involves nearly 600 current or former heavy smokers aged 50-77. The goal is to see if coaching leads to more screening…

This study is testing whether using a virtual reality (VR) headset can help young adults with ADHD concentrate better while doing homework and studying. Researchers are comparing three approaches: using a VR headset normally, using it with real-time feedback on focus, and a contr…

This study is testing whether an AI-powered chatbot can effectively deliver a proven therapy to help prevent suicide. It will involve 50 older adults living with HIV who are at risk for suicide. The goal is to see if this accessible, digital approach helps people better manage di…

This study is testing whether Latin dance classes can help improve sleep quality for Hispanic cancer survivors who struggle with poor sleep. Researchers will enroll 40 physically inactive Hispanic adults who have finished their main cancer treatment but still experience sleep pro…

This study is testing a simple dental injection, called the Twin Block, to see if it can effectively reduce jaw muscle pain after wisdom tooth removal. The goal is to provide a safe, non-opioid option for pain control to help address the national opioid crisis. Researchers will e…

This study aims to find out which method works better for controlling pain after common outpatient orthopedic surgeries like ACL reconstruction and rotator cuff repair. Researchers will compare a continuous pain pump that delivers medication over several days to a single nerve-bl…

This study is testing whether a smartphone app that teaches better sleep habits can help reduce suicidal thoughts in teenagers. Researchers are enrolling 80 teens, aged 14-18, who were recently hospitalized for suicide risk and also have trouble sleeping. Half will use the 'Sleep…

This study is testing a special numbing injection, called the Temporo-masseteric Nerve Block (TMNB), given right after wisdom tooth removal. The goal is to see if it can reduce post-surgery pain and the need for strong opioid painkillers. Researchers will follow 20 participants f…

This study is testing whether giving higher doses of radiation over 10 treatments can provide better and longer-lasting pain relief for people with cancer that has spread to bones or other areas. The trial aims to see if this approach increases the number of patients who become c…

This study is testing whether Cognitive Behavioral Therapy for Insomnia (CBT-I) helps older African American adults sleep better. Participants will either receive 8 weekly video sessions teaching sleep strategies or a single educational session. Researchers will measure sleep qua…

This study is testing if applying a special gel called RADA16 during tonsil removal surgery helps patients recover better. Researchers want to see if the gel reduces pain, bleeding, and the need for strong painkillers after the operation. About 134 adults having a tonsillectomy w…

This study is testing if a numbing injection given during surgery for non-cancerous vocal cord growths helps patients recover better. Researchers will compare the numbing shot to a placebo (saltwater) injection. They will measure if it reduces pain and coughing after surgery and …

This study aims to find the best type of non-invasive brain stimulation to change how the brain responds to rewards in people who smoke. Researchers will test different stimulation patterns on 42 participants to see their effects on brain activity, decision-making, and cravings. …

This study aims to find the most effective spot in the brain to stimulate with a non-invasive magnet (TMS) to help people with nicotine addiction. Researchers will test four different brain targets in 36 smokers to see which one best changes how the brain responds to rewards and …

This online research study aims to understand how genetics influence a person's risk of developing pulmonary hypertension, a condition affecting blood pressure in the lungs. The study is recruiting 10,000 adults living in the United States, and participants do not need to have a …

This study aims to understand if a non-invasive brain stimulation technique (TMS) can change how people process rewards and learn from them during simple computer games. Researchers will measure brain waves in healthy adults while they perform decision-making tasks, with some rec…

This study aims to understand how breathing ozone, a common air pollutant, causes lung injury. Healthy volunteers will breathe filtered air and a low level of ozone on separate visits while doing light exercise. Researchers will collect mucus samples from participants' lungs afte…

This study aims to see if a specially designed chatbot can help Black cancer survivors learn about and request genetic testing for hereditary cancer risk. Researchers will compare the chatbot to standard educational materials to see which method is more effective. The goal is to …

This study aims to understand how a person's body composition (like muscle and fat) affects the levels of immunoglobulin medication in their blood. It will enroll 20 adults with a nerve disorder called CIDP who receive this medication. Researchers will measure drug levels after p…

This study aims to understand how tiny particles in the blood, called extracellular vesicles, affect blood vessel function in people with type 2 diabetes. Researchers will study 60 adults with and without diabetes to see if these particles harm blood vessels and if regular exerci…

This online research study aims to understand how genes influence a person's risk of developing kidney disease. It is open to any adult living in the US, whether they have kidney disease or not. Participants complete a 20-minute health survey online and mail in a saliva sample us…

This study aims to understand how a non-invasive brain stimulation technique affects how people learn and remember locations. Healthy adult participants will play virtual maze games while receiving either real or fake magnetic pulses to a specific part of their brain. Researchers…

This study aims to understand how attention and thinking strategies affect decision-making in people with schizophrenia or schizoaffective disorder. Researchers will compare brain activity during gambling tasks and track real-world choices through daily surveys. The goal is to le…

This study aims to learn how a specific nerve-blocking injection for the jaw muscles works. Researchers will give the injection to 20 healthy volunteers and measure changes in their bite force and jaw muscle activity. The goal is to understand why this injection might relieve jaw…

This study aims to understand how a common type of breast cancer (HR+/HER2-) uses nutrients like sugar and fat to grow. During their scheduled cancer surgery, 16 participants will receive a special glucose infusion. Researchers will then collect small samples of their tumor and n…

This study aims to understand how different ways of asking about resuscitation preferences affect the choices hospitalized patients make. Researchers will test whether including the word 'death' in the question changes the answer, and see if doctors agree with their patients' dec…

This research study aims to understand how the decisions we make affect our short-term memory. Researchers will record brain activity from 50 patients who are already having electrodes implanted for epilepsy treatment. By having participants play computer games that test decision…

This study is testing a new online training program called DECIDE, designed to help healthcare providers improve how they discuss mental health treatment options with pregnant and postpartum patients. The research team will adapt an existing training and then ask about 35 nurses,…

This study aims to understand if an educational workshop can change women's knowledge and behaviors regarding the chemicals in hair products. Researchers will survey about 120 women in Newark, New Jersey, before and after they attend a 'clean beauty' class. The goal is to see if …

This online research study aims to better understand how genes affect a person's risk of developing breast cancer. Researchers are recruiting 25,000 adults living in the US to complete health surveys and provide a saliva sample by mail. The goal is to discover new genetic links t…