Could a common allergy pill ease bone pain in myeloma treatment?

NCT ID NCT04211259

Recruiting now Symptom relief Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early trial is testing whether loratadine, better known as the allergy medicine Claritin, can reduce bone pain caused by a drug called G-CSF in people with multiple myeloma who are having their stem cells collected. The study will compare pain levels between those taking loratadine and those taking a placebo. If successful, it could provide a simple, low-cost way to manage a common side effect of stem cell mobilization.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: loratadine (Claritin)
What this could lead to: If it works, this could offer a simple, over-the-counter option to reduce bone pain during stem cell collection for multiple myeloma patients.
What could go wrong: This is a very early phase 1 trial with only 70 participants, so results may not be conclusive. The pain relief may be minimal or no better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLASMA CELL MYELOMA

Contacts and locations

Locations

RWJBarnabas Health - Robert Wood Johnson University Hospital, New Brunswick
NOT_YET_RECRUITING

New Brunswick, New Jersey, 08903, United States
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States

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