Body fat may change how well immune therapy works

NCT ID NCT05584631

Recruiting now Knowledge-focused Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a person's body composition (fat and muscle) affects the way immunoglobulin G (IgG) moves through the body after being given through a vein or under the skin. Researchers will enroll 20 adults with a nerve condition called CIDP who already receive IgG therapy. The goal is to see if current dosing is adequate for people with very high or low body weight.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Immune globulin G (IVIG and SCIG)
What this could lead to: If successful, this could lead to more personalized dosing of immunoglobulin therapy for people with CIDP, especially those with extreme body weights.
What could go wrong: This is a very small, early-phase study (20 people) focused on drug levels, not on treatment outcomes. Results may not change current practice or apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agammaglobulinemia chronic inflammatory demyelinating polyradiculoneuropathy Obesity polyneuropathy, inflammatory demyelinating, chronic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY CIDP IMMUNOGLOBULIN DEFICIENCY

Contacts and locations

Locations

Rutgers, The State University of New Jersey Clinical Research Center
RECRUITING

New Brunswick, New Jersey, 08901, United States

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