Body fat may change how well immune therapy works

NCT ID NCT05584631

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a person's body composition (fat and muscle) affects the way immunoglobulin G (IgG) moves through the body after being given through a vein or under the skin. Researchers will enroll 20 adults with a nerve condition called CIDP who already receive IgG therapy. The goal is to see if current dosing is adequate for people with very high or low body weight.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Immune globulin G (IVIG and SCIG)

What this could lead to

If successful, this could lead to more personalized dosing of immunoglobulin therapy for people with CIDP, especially those with extreme body weights.

What could go wrong

This is a very small, early-phase study (20 people) focused on drug levels, not on treatment outcomes. Results may not change current practice or apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agammaglobulinemia chronic inflammatory demyelinating polyradiculoneuropathy Obesity polyneuropathy, inflammatory demyelinating, chronic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rutgers, The State University of New Jersey Clinical Research Center

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••