Rutgers, The State University Of New Jersey

This phase 2 trial tests whether giving hormone therapy before prostate surgery helps men with high-risk prostate cancer recover erectile function better. About 90 men will receive either apalutamide alone or a combination of apalutamide, abiraterone, GnRH agonist, and prednisone…

This study tests whether a jaw muscle nerve block (Twin block) and a smart pill dispenser (iPill) can reduce opioid use after wisdom tooth removal. About 133 adults will be enrolled. The nerve block aims to ease pain right after surgery, while the dispenser only releases opioids …

This study was designed to see if giving two chemotherapy drugs (gemcitabine and capecitabine) after surgery could help people with pancreatic cancer stay cancer-free longer. It was for patients who had already received chemotherapy before surgery. However, the trial was withdraw…

This study tests whether giving antibiotics directly into the bone (intraosseous) during hip replacement surgery can increase antibiotic levels in blood and tissue compared to standard IV antibiotics alone. About 25 adults having a first-time hip replacement will receive either t…

This phase 2 trial tests whether pembrolizumab (Keytruda) can shrink or control advanced solid tumors that have certain gene mutations (BRCA1, BRCA2, POLE, POLD1). The study enrolled 21 adults with cancers that have spread or come back. Researchers measure how many patients see t…

This phase 2 trial was designed to test a combination of rituximab, venetoclax, and bortezomib in patients with diffuse large B-cell lymphoma that had come back or stopped responding to treatment. The goal was to see how many patients would have their tumors shrink or disappear. …

This phase II trial is testing whether giving the immunotherapy drug pembrolizumab before standard chemotherapy and radiation can help prevent stomach cancer from coming back. It includes 40 people with operable stomach cancer that has either a specific DNA repair problem (mismat…

This study tests a 1-month course of three medicines (isoniazid, rifapentine, and vitamin B6) to treat latent tuberculosis in 25 adults with end-stage kidney disease who are candidates for a kidney transplant. The goal is to see if this shorter treatment is safe and easy to compl…

This study tests whether giving an extra dose of radiation (a boost) before breast cancer surgery is safe and helpful. About 103 people with early-stage breast cancer that hasn't spread will receive the boost, then standard radiation and surgery. The goal is to see if this approa…

This study tests whether giving a powerful mix of chemotherapy and radiation before surgery can completely eliminate rectal cancer in more patients. About 38 adults with rectal cancer will receive the experimental treatment and be followed for up to 4 years. The goal is to see if…

This study tests whether giving a short course of radiation to part of the breast before surgery is safe and practical for women with early-stage breast cancer. About 98 women over age 50 with small, hormone-sensitive tumors will receive radiation, then have surgery. Researchers …

This phase II trial compares two types of radiation therapy for men with early-stage prostate cancer that hasn't spread. One method places a radioactive seed directly into the prostate for a few minutes, while the other delivers radiation from outside the body in five sessions. T…

This study tests whether DHA, a key omega-3 fatty acid found in fish oil, can improve symptoms of autism in children and adolescents aged 5 to 17. Participants receive either DHA or a placebo daily for 12 weeks. Researchers also look at genes and urine markers related to DHA to u…

This study looks at whether updating radiation treatment plans at set times (adaptive planning) can lower side effects like lung inflammation in people with stage II-IV non-small cell lung cancer. About 34 participants will receive standard radiation and immunotherapy, but their …

This study tests whether a smartphone app can help adults who are hospitalized for depression or suicidal thoughts. After leaving the hospital, participants use the app for 28 days to practice skills that encourage positive activities. The goal is to see if the app is easy to use…

This study tests whether simple behavioral strategies can help college students reduce problematic smartphone use. Fifty students who feel they use their phones too much will try a mobile app that tracks social media and gaming time, encourages alternative activities, and offers …

This early-stage study tests whether a low dose of colchicine, a medicine usually used for gout, can safely reduce skin redness and pain caused by radiation therapy in people with head and neck cancer. About 30 participants take one pill daily during their radiation treatment. Th…

This study tests a series of 14 animated videos that teach coping skills based on Dialectical Behavior Therapy (DBT). The videos are available in English and Mandarin and are designed for Chinese and Chinese American college students. Researchers want to see if watching these vid…

This study looks at whether a combination of over-the-counter pain relievers (like ibuprofen and acetaminophen) can control pain after wisdom tooth removal just as well as, or better than, prescription opioids. About 1,800 people having their wisdom teeth removed will be randomly…

This study tests an online program called Empowered Survivor, designed to help people who have had oral or throat cancer feel more confident managing their health after treatment. Researchers are comparing it to a free online tool already available for cancer survivors. The goal …

This study tests whether a nerve block given before heart surgery can reduce pain and the need for opioid painkillers afterward. About 150 adults having heart surgery will receive either a long-acting or standard form of the numbing drug bupivacaine via ultrasound-guided injectio…

This study tests whether a daily drink of freeze-dried grape powder can reduce anxiety, depression, and stress in healthy college students aged 18-30. Over 4 weeks, 50 participants will take either the grape powder or a placebo and complete surveys and stool tests. The goal is to…

This study looks at whether having a radiation oncologist involved early in care, alongside standard treatment, can improve quality of life for people with metastatic cancer. About 156 adults with cancer that has spread and is not curable will be randomly assigned to either stand…

This study is testing a program called Journey Ahead, designed to help women with gynecologic cancers improve their coping and communication skills. The researchers are enrolling 30 women who have been diagnosed with ovarian, endometrial, cervical, or uterine cancer. Participants…

This phase 2 trial tests whether sulforaphane, a compound found in broccoli, can improve core symptoms of autism. 48 males aged 13-30 with autism will receive either sulforaphane or a placebo for several weeks. Researchers will measure changes in behavior and social responsivenes…

This study looks at ways to help more adults with type 2 diabetes get screened for colorectal cancer. Researchers are testing a program that works with patients, their care teams, and clinics to make screening easier. The goal is to see if this approach increases the number of pe…

This study looks at whether Facebook groups can help young people diagnosed with melanoma (ages 18-39) and their close relatives do more skin exams and sun protection. About 1,160 participants will join either a melanoma-focused Facebook group or a healthy lifestyle Facebook grou…

This study uses smartphone data to understand what triggers anxiety and alcohol use in each person, then tailors therapy to those specific triggers. 81 adults with anxiety and alcohol problems will receive 11 sessions of cognitive behavioral therapy (CBT) either personalized to t…

This study tests a 10-week educational program called HomeStyles-China, designed to help Chinese American adults improve their diet, increase physical activity, and reduce risk factors for heart disease and diabetes. Researchers will enroll 400 participants and measure changes in…

This study tests a program to improve follow-up care for breast cancer survivors in primary care clinics. The program includes training, expert advice, and feedback for clinic staff. Researchers will see if it helps clinics provide more complete care for managing symptoms and lon…

This study is for people with gastrointestinal cancer that has spread to the lining of the abdomen. Researchers will collect tumor tissue and blood samples to create a custom blood test that looks for cancer DNA. The goal is to see if this test can help doctors monitor the cancer…

This study tests whether a family wellness program helps Latino children entering kindergarten improve their language, literacy, and social-emotional skills. The program includes 8 weekly summer workshops, booster sessions, and text messages over 10 months. Researchers will compa…

This study aimed to develop and test a smartphone app to help patients use, store, and dispose of opioid pain medications safely. It planned to include focus groups and a small trial with a reward system. However, the study was withdrawn before enrolling any participants, so no d…

This study tests a digital self-management and peer mentoring program for young adults who survived childhood cancer. The goal is to help them take charge of their own health care as they move from pediatric to adult clinics. About 300 survivors aged 18-25 will use the program to…

This pilot study is testing whether a personalized blood test that looks for leftover tumor DNA can help doctors make better treatment decisions for people with early-stage breast cancer. About 34 participants with triple-negative or HER2-positive breast cancer will receive chemo…

This small pilot study aims to see if digital biomarkers—like heart rate and movement tracked by a watch—can help measure changes in autism symptoms during treatment with sulforaphane, a compound found in vegetables. Ten males aged 13-30 with autism who previously took part in a …