Sleep hormone may shield kidneys from antibiotic harm

NCT ID NCT05084196

Recruiting now Prevention Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether melatonin, a common sleep aid, can prevent kidney damage in hospitalized patients who need a strong antibiotic called vancomycin. About 300 adults aged 18 to 75 will receive either melatonin or a placebo alongside their antibiotic. The goal is to see if melatonin reduces the risk of acute kidney injury, a serious side effect of this treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE KIDNEY INJURY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute kidney injury Drug-Related Side Effects and Adverse Reactions acute tubulointerstitial nephritis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY ADVERSE DRUG EVENT

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Robert Wood Johnson University Hospital
RECRUITING

New Brunswick, New Jersey, 08901, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Robert Wood Johnson University Hospital Somerset
RECRUITING

Somerville, New Jersey, 08876, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact