Could a stronger starting dose of buprenorphine get more people into opioid addiction treatment?

NCT ID NCT05589181

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study tests whether giving a higher-than-standard dose of buprenorphine (a medication for opioid use disorder) in the emergency department is safe and helps more people start addiction treatment within a week. About 140 adults with moderate to severe opioid use disorder who test positive for fentanyl will take part. The goal is to see if a 32 mg dose works better than the usual 12 mg dose at getting patients into ongoing care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rutgers University Hospital

    RECRUITING

    Newark, New Jersey, 07103, United States

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