Could a stronger starting dose of buprenorphine get more people into opioid addiction treatment?

NCT ID NCT05589181

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving a higher-than-standard dose of buprenorphine (a medication for opioid use disorder) in the emergency department is safe and helps more people start addiction treatment within a week. About 140 adults with moderate to severe opioid use disorder who test positive for fentanyl will take part. The goal is to see if a 32 mg dose works better than the usual 12 mg dose at getting patients into ongoing care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rutgers University Hospital

    RECRUITING

    Newark, New Jersey, 07103, United States