Can more radiation zap cancer pain faster?

NCT ID NCT05419518

Recruiting now Symptom relief Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether a higher dose of radiation (40-50 Gy over 10 sessions) can better relieve pain from cancer that has spread to bones or other areas. Researchers hope to double the complete pain response rate at one month compared to standard doses. The study involves 124 adults with a life expectancy of at least six months and aims to balance pain relief with safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: external beam radiation
What this could lead to: If successful, this could offer a more effective and longer-lasting pain relief option for people with cancer that has spread to bones or other tissues.
What could go wrong: This is an early-phase trial with only 124 participants, so results may not apply to everyone. Higher radiation doses also carry increased risk of side effects like fatigue or local tissue damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone cancer metastatic carcinoma in the bone metastatic neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTASES, NEOPLASM NEOPLASM METASTASES

Contacts and locations

Locations

Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States
RWJBarnabas Health - Community Medical Center
RECRUITING

Toms River, New Jersey, 08755, United States
RWJBarnabas Health - Monmouth Medical Center Southern Campus
RECRUITING

Lakewood, New Jersey, 08701, United States
RWJBarnabas Health - Robert Wood Johnson University Hospital
NOT_YET_RECRUITING

Hamilton, New Jersey, 08690, United States
RWJBarnabas Health - Robert Wood Johnson University Hospital
RECRUITING

Somerset, New Jersey, 08876, United States
RWJBarnabas Health - Saint Barnabas Medical Center
RECRUITING

Livingston, New Jersey, 10457, United States
Robert Wood Johnson University Hospital
RECRUITING

New Brunswick, New Jersey, 08901, United States

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