Can more radiation zap cancer pain faster?
NCT ID NCT05419518
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether a higher dose of radiation (40-50 Gy over 10 sessions) can better relieve pain from cancer that has spread to bones or other areas. Researchers hope to double the complete pain response rate at one month compared to standard doses. The study involves 124 adults with a life expectancy of at least six months and aims to balance pain relief with safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
external beam radiation
What this could lead to
If successful, this could offer a more effective and longer-lasting pain relief option for people with cancer that has spread to bones or other tissues.
What could go wrong
This is an early-phase trial with only 124 participants, so results may not apply to everyone. Higher radiation doses also carry increased risk of side effects like fatigue or local tissue damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cancer Institute of New Jersey
RECRUITINGNew Brunswick, New Jersey, 08903, United States
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RWJBarnabas Health - Community Medical Center
RECRUITINGToms River, New Jersey, 08755, United States
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RWJBarnabas Health - Monmouth Medical Center Southern Campus
RECRUITINGLakewood, New Jersey, 08701, United States
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RWJBarnabas Health - Robert Wood Johnson University Hospital
NOT_YET_RECRUITINGHamilton, New Jersey, 08690, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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RWJBarnabas Health - Robert Wood Johnson University Hospital
RECRUITINGSomerset, New Jersey, 08876, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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RWJBarnabas Health - Saint Barnabas Medical Center
RECRUITINGLivingston, New Jersey, 10457, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Robert Wood Johnson University Hospital
RECRUITINGNew Brunswick, New Jersey, 08901, United States