Can a new capsule ease bone metastasis pain without opioids?
NCT ID NCT07731685
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This trial tests an experimental drug called VC004 for people with moderate-to-severe pain caused by cancer that has spread to the bones. About 26 adults will receive either a low or high dose of VC004 or a placebo capsule, and researchers will track changes in daily pain scores over time. The goal is to see whether VC004 is safe and whether it can reduce pain intensity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental drug called VC004, taken as a capsule
- What this could lead to
- If it works, this could offer a new pain-relief option for people with cancer that has spread to their bones.
- What could go wrong
- This is an early, small trial testing safety and dosing — it is not yet known whether VC004 works better than a placebo. Possible side effects are still being identified.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BONE METASTASES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Zhongda Hospital,Affiliated to Southeast University
Nanjing, Jiangsu, China
-
Zhongda Hospital,Affiliated to Southeast University
Nanjing, Jiangsu, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Preventive radiation may stop bone events before they start — a trial puts it to the test
- Hip muscle repair method may improve walking after bone cancer surgery
- New model aims to predict jaw bone disease before it strikes
- Could removing the primary tumor boost survival in stage IV breast cancer with Bone-Only spread?
- New 25-Minute bone scan could spot cancer faster with less radiation
- Can bone markers predict survival in lung cancer patients?