Can a new capsule ease bone metastasis pain without opioids?

NCT ID NCT07731685

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests an experimental drug called VC004 for people with moderate-to-severe pain caused by cancer that has spread to the bones. About 26 adults will receive either a low or high dose of VC004 or a placebo capsule, and researchers will track changes in daily pain scores over time. The goal is to see whether VC004 is safe and whether it can reduce pain intensity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental drug called VC004, taken as a capsule
What this could lead to
If it works, this could offer a new pain-relief option for people with cancer that has spread to their bones.
What could go wrong
This is an early, small trial testing safety and dosing — it is not yet known whether VC004 works better than a placebo. Possible side effects are still being identified.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Zhongda Hospital,Affiliated to Southeast University

    Nanjing, Jiangsu, China

  • Zhongda Hospital,Affiliated to Southeast University

    Nanjing, Jiangsu, China

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