Could removing the primary tumor boost survival in stage IV breast cancer with Bone-Only spread?
NCT ID NCT07687225
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial investigates whether surgically removing the primary breast tumor, followed by standard systemic therapy, improves survival compared to systemic therapy alone in women with stage IV breast cancer that has spread only to a single bone site. The study enrolls women aged 18 to 70 with newly diagnosed or first-line-treated disease. Researchers will track overall survival, cancer progression, quality of life, and treatment side effects over five years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Primary tumor resection (surgery)
- What this could lead to
- If surgery plus systemic therapy improves survival, it could become a new standard approach for patients with stage IV breast cancer that has spread only to bone.
- What could go wrong
- This is a randomized trial, but the benefit of surgery in stage IV cancer is unproven. Surgery carries risks like infection or complications, and the cancer may still progress despite treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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