Sugar tracking study aims to unlock breast Cancer's fuel secrets

NCT ID NCT05736367

Recruiting now Knowledge-focused Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study looks at how hormone receptor positive/HER2 negative breast cancer uses glucose and other nutrients for energy. Sixteen participants with early-stage breast cancer will receive a special labeled sugar infusion before surgery. Researchers will then analyze tumor and healthy tissue samples to map metabolic pathways, which could help identify new treatment targets in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: U-13C-glucose (a special labeled sugar given by infusion to track how tumors use energy)
What this could lead to: If successful, this study could reveal new metabolic targets for treating HR+/HER2- breast cancer, potentially leading to more effective therapies.
What could go wrong: This is a very small pilot study (16 people) with no treatment being tested. It only aims to understand metabolism, not to cure or control the disease. Results may not lead to any practical changes.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

RWJBarnabas Health
NOT_YET_RECRUITING

New Brunswick, New Jersey, 08903, United States
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States

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