Insel Gruppe Ag, University Hospital Bern

This study aims to find out if performing a second brain surgery when an aggressive brain tumor (glioblastoma) comes back helps patients live longer and maintain a better quality of life. It will compare two groups: one that has surgery followed by standard drug therapy, and anot…

This European study tests a patient-centered program to help adults 65+ safely reduce or stop long-term use of sleeping pills like benzodiazepines. The program provides doctors with training and materials to support patients through the process while monitoring sleep quality and …

This study is testing a new training program designed to help children and teenagers with ADHD. The program combines thinking exercises with physical coordination tasks to strengthen long-term brain development and self-awareness. Researchers want to see if this approach improves…

This study is testing whether removing the entire pancreas is better than removing just part of it for patients with cancer in the head of the pancreas who are at high risk of a dangerous leak after surgery. Researchers will randomly assign 170 patients to receive either the stan…

This study is testing if a special exercise and education program can help people recover better after a serious lung clot (pulmonary embolism). Many patients still feel tired, short of breath, and have a poor quality of life months later, even with standard blood thinner medicat…

This study is observing how well a higher-dose version of an existing eye injection (aflibercept 8mg) works in the first two months for people with 'wet' age-related macular degeneration (AMD). Researchers will track how quickly fluid in the back of the eye decreases and if visio…

This study is testing if using a personalized risk calculator helps doctors decide the best length of time for patients to take two blood-thinning drugs after getting a heart stent. It will compare this calculator-guided approach to the current standard where doctors decide based…

This international trial is testing whether adding high-dose steroids to standard aspirin treatment helps children recover better from a stroke caused by inflamed brain arteries. About 70 children across multiple countries will be randomly assigned to receive either steroids plus…

This study is for people with atrial fibrillation (AFib) who have had a stroke despite taking blood thinners. It tests if adding a heart procedure to close a small pouch in the heart (called the left atrial appendage) is better than just continuing blood thinners alone. The goal …

This study is testing whether the type of IV fluid given to patients after a serious brain bleed affects their recovery. Researchers are comparing a salt-rich fluid (normal saline) to a more balanced fluid (lactated Ringer's) to see which one better prevents dangerous blood vesse…

This study is testing whether adding a special electrical stimulation therapy to standard hand therapy can improve arm and hand function in children with hemiparesis (weakness on one side of the body). Children aged 6-18 will use a glove or electrodes at home for 30 minutes a day…

This study is testing if adding a small amount of fluid into the chest space during a CT-guided lung biopsy can reduce the risk of the lung collapsing, a common complication. Researchers will also check if positioning the patient so the biopsy is taken from the lower part of the …

This study is testing a questionnaire for families to fill out, called QUOCCAS, to see if it can accurately identify children with cancer who might have an inherited risk for the disease. It will compare the questionnaire's results to standard doctor assessments and genetic testi…

This study aims to see if a newer MRI contrast agent (gadopiclenol) works as well as the current standard agent (gadobutrol) for getting clear pictures of the kidneys and adrenal glands. About 104 adults with incidental findings on these organs will be randomly assigned to receiv…

This study is testing whether a smartphone app that coaches parents can help lower obesity risk in children aged 6-12 who have a high body mass index (BMI). 148 children in Switzerland will be randomly assigned to either receive standard care or standard care plus the app for the…

This study is testing whether hormone replacement therapy (HRT) or cognitive behavioral therapy (CBT) works better to reduce insomnia in women going through perimenopause. Researchers will compare these two treatments against basic sleep hygiene advice in 54 participants. Women w…

This study is testing whether a nasal spray containing the drug midazolam can safely and quickly reduce acute anxiety in hospitalized patients receiving palliative care. It will involve 36 patients who will receive either one of two different doses of the spray or a placebo (a sp…

This study aims to find out if the common painkiller paracetamol (acetaminophen) is actually needed for people with chronic cancer pain who are already taking strong opioid medications. About 140 adult patients currently taking both medications will be randomly assigned to either…

This study is testing a smartphone app designed to help children and teenagers who have had cancer. The app provides training exercises to improve long-term thinking, memory, and physical coordination problems that can occur after cancer treatment. Researchers want to see if usin…

This study aims to understand what affects recovery and pain after weight-loss surgery. Researchers will follow 2,000 patients for up to 5 years, collecting information on their pain levels, side effects, and how surgery impacts their daily life and quality of life. The goal is t…

This study aims to understand if hormone replacement therapy (HRT) affects how often and how severely post-menopausal women get respiratory infections like colds and flu. Researchers will follow 400 women aged 40-60 for six months, tracking infections and collecting data from sma…

This study aims to find out if removing the main tumor helps patients with advanced small intestinal neuroendocrine tumors that have spread and cannot be cured. It will compare the long-term survival and complication rates of patients who had surgery to those who received medicat…

This Swiss study is following hundreds of patients who develop an infection after a hip, knee, or other joint replacement. Researchers will track patients for at least two years to see which treatments work best and what factors—like a patient's health or the type of bacteria—lea…

This study aims to improve how doctors assess tissue firmness, a common part of physical exams. Medical professionals and students will practice feeling and measuring firmness on artificial tissue models using both their hands and ultrasound machines. Researchers will compare the…

This study aims to understand why some people experience more pain after surgery than others. Researchers will observe 5,000 adults having elective surgery to see if their genes, along with other factors, are linked to severe pain, high painkiller use, or long-term pain. The goal…

This study aims to understand why some people with atrial fibrillation (AF, an irregular heartbeat) still have a stroke even while taking blood-thinning medication. Researchers will follow 500 stroke patients with AF for about a year, collecting blood samples and heart scan data.…

This study aims to understand why some people have more complications after surgery than others. Researchers will follow 20,000 adults having planned surgery to see if factors like a person's genetics, the type of surgery, or anesthesia used are linked to problems like severe nau…

This study is testing a new online education and self-management program for people with fibrotic interstitial lung disease (FILD), a condition that causes lung scarring. Researchers want to see if patients find the program useful and practical to use during their hospital rehabi…

This large European study aims to understand how often breathing tube problems occur during anesthesia and what causes them. Researchers will observe 40,000 adult patients across multiple hospitals to track both minor and serious airway incidents. The goal is to collect data that…

This study tests whether a structured communication tool called the StOP?-protocol improves patient safety during surgery. Surgeons are randomly assigned to either use this checklist or communicate as usual during operations. Researchers will compare patient outcomes like death r…

This early-stage study aims to understand how two common oral blood thinners (rivaroxaban and apixaban) are processed by the body in people with compensated liver cirrhosis. It will enroll 24 participants who will receive a single dose of one medication, followed by multiple bloo…

This study aims to understand how multiple sclerosis affects brain aging by comparing advanced MRI scans of 200 people—half with MS and half healthy. Researchers will measure brain age using special imaging techniques and see how it relates to symptoms like walking difficulty, fa…