New hope for kidney stone sufferers: Longer-Acting drugs may offer better prevention

NCT ID NCT06111885

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two long-acting drugs, indapamide and chlorthalidone, to the standard short-acting drug hydrochlorothiazide for preventing calcium kidney stones. About 99 adults who have had at least two kidney stones in the past 10 years will participate. The goal is to see if the longer-acting drugs reduce stone-forming substances in urine more effectively.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Inselspital, Department of Nephrology and Hypertension

    RECRUITING

    Bern, 3010, Switzerland

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