Could your diet trigger kidney stones by changing your immune system?
NCT ID NCT04051346
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at how eating high or low amounts of oxalate (a natural compound in many foods) affects urine crystals and immune cells in healthy adults. Fourteen participants followed two controlled diets to see if oxalate changes crystal formation and immune function. The goal is to better understand how diet might lead to kidney stones.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Low Oxalate Diet and High Oxalate Diet
What this could lead to
If successful, this could reveal how diet influences the immune system's role in kidney stone formation, pointing toward future prevention strategies.
What could go wrong
This is a small, early-stage study with only 14 healthy participants, not patients. Results may not apply to people with kidney stones or other conditions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States