Can a simple heart rate drug prevent Surgery-Related heart attacks?

NCT ID NCT07168421

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether the drug landiolol can safely keep heart rate below 90 beats per minute during major surgery in 114 patients with heart risks. The goal is to see if this approach is feasible and might reduce heart injury after surgery. Participants receive the drug through an IV during and after their operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Landiolol (a short-acting beta-blocker given intravenously)

What this could lead to

If successful, this could show that controlling heart rate during surgery reduces heart damage in at-risk patients, paving the way for a larger trial.

What could go wrong

This is a small feasibility trial, not designed to prove effectiveness. The drug may cause low blood pressure or require additional medications. Results may not apply to all surgery types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

primary dysautonomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bern University Hospital, Freiburgstrasse

    RECRUITING

    Bern, 3010, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••