Can a simple heart rate drug prevent Surgery-Related heart attacks?
NCT ID NCT07168421
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether the drug landiolol can safely keep heart rate below 90 beats per minute during major surgery in 114 patients with heart risks. The goal is to see if this approach is feasible and might reduce heart injury after surgery. Participants receive the drug through an IV during and after their operation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Landiolol (a short-acting beta-blocker given intravenously)
- What this could lead to
- If successful, this could show that controlling heart rate during surgery reduces heart damage in at-risk patients, paving the way for a larger trial.
- What could go wrong
- This is a small feasibility trial, not designed to prove effectiveness. The drug may cause low blood pressure or require additional medications. Results may not apply to all surgery types.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bern University Hospital, Freiburgstrasse
RECRUITINGBern, 3010, Switzerland
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