Hidden heart risk: routine cancer scans could reveal cardiovascular danger in breast cancer survivors

NCT ID NCT07703033

Recruiting now Knowledge-focused Sponsor: UMC Utrecht Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether measuring calcium buildup in heart arteries from routine radiotherapy planning CT scans can identify breast cancer patients at risk for heart disease. Researchers will share this personalized risk information with patients and their doctors to see if it influences treatment decisions and patient satisfaction. The goal is to improve long-term heart health in breast cancer survivors without extra scans or radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: measuring coronary artery calcifications (Agatston score) using routine radiotherapy planning CT scans and communicating the associated risk of cardiovascular disease to the patient
What this could lead to: If successful, this approach could help identify breast cancer patients at high risk for heart disease earlier, leading to better preventive care and improved long-term health.
What could go wrong: This is a decision-impact study, not a treatment trial. It measures whether sharing risk information changes care, but it may not directly improve health outcomes. Some patients may experience anxiety from learning their heart risk.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm ductal breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER CARDIOVASCULAR (CV) RISK CORONARY ARTERY CALCIFICATIONS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Amsterdam University Medical Center
NOT_YET_RECRUITING

Amsterdam, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••
Champalimaud Foundation
NOT_YET_RECRUITING

Lisbon, Portugal

Contact Phone: •••-•••-•••• Email: •••••@•••••
LMU University Hospital
NOT_YET_RECRUITING

München, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
RegionH
NOT_YET_RECRUITING

Copenhagen, Denmark

Contact Phone: •••-•••-•••• Email: •••••@•••••
St. Antonius Hospital
RECRUITING

Utrecht, Netherlands

Contact Email: •••••@•••••

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