Insel Gruppe Ag, University Hospital Bern

This study tests two approaches to prevent kidney stones from coming back in people who have had them before. One approach uses a daily pill called empagliflozin (a diabetes drug) and the other gives personalized diet advice based on urine tests. The trial will involve 400 adults…

This study tests whether people with giant cell arteritis (GCA) can safely take steroids for only 8 weeks instead of the usual 26 weeks when also using the drug tocilizumab. About 178 participants will be randomly assigned to one of two treatment lengths. The goal is to see if th…

This study tests whether semaglutide (a GLP-1 drug used for diabetes and weight loss) can help people with obesity and fatty liver disease reduce or stop drinking alcohol. 64 participants will receive either semaglutide injections plus lifestyle counseling, or counseling alone. T…

This study tests whether a single injection of fremanezumab, a drug used to prevent migraines, can stop acute mountain sickness (AMS) in healthy adults. Thirty volunteers will receive either the drug or a placebo one week before climbing to a high-altitude hut. Researchers will t…

This trial tests whether a 12-week home rehabilitation program using the Akina app is as effective as standard outpatient physiotherapy for older adults (ages 55-80) recovering from hip surgery. Sixty-six participants will either use the digital program at home or receive routine…

This study tests whether adding the drug dexmedetomidine during carotid artery surgery helps keep blood pressure more stable. About 44 adults having this surgery will be randomly assigned to receive either standard anesthesia alone or standard anesthesia plus dexmedetomidine. The…

This study tests whether the Stockholm3 blood test can accurately detect when low-risk prostate cancer becomes more aggressive in men who are closely monitored instead of treated immediately. Researchers will enroll 350 men on active surveillance to see if the test can reduce the…

This study looks at how sleep apnea measurements change from night to night. Current tests rely on a single night, which can be inaccurate. Researchers will track 192 people over multiple nights to find more reliable markers for diagnosis and treatment.

This study will compare how synthetic nicotine and a nicotine analogue (6-methylnicotine) behave in the body versus traditional tobacco-derived nicotine. Twenty-four regular vapers will vape e-liquids containing these substances, and researchers will measure their levels in the b…

This study asks children aged 6-16, their parents, and clinicians to vote on the most important research topics in pediatric anesthesia and perioperative medicine. Over 1,000 participants in Switzerland will complete online surveys to create a ranked list of the top 10 priorities…

This study looks at whether turning on a cochlear implant affects a person's sense of direction and balance. Seven hundred adult cochlear implant users will take online surveys and perform balance tests under different implant settings. The goal is to see if the implant's sound c…