Insel Gruppe Ag, University Hospital Bern

This trial tests whether a newer cryoballoon device, PolarX, works as well as the standard Arctic Front device for treating paroxysmal atrial fibrillation (a type of irregular heartbeat). About 200 people having their first pulmonary vein isolation procedure will be randomly assi…

This study looked at whether a newer type of deep brain stimulation (DBS) electrode, which can steer electrical signals more precisely, improves mood and movement in people with Parkinson's disease. 105 participants received the directional electrodes as part of their standard ca…

This study tested a structured plan to remove excess fluid early in patients with septic shock. 170 ICU patients were randomly assigned to either the fluid removal protocol or standard care. The goal was to see if the plan could safely reduce fluid buildup by day three, which mig…

This phase 3 trial tested whether giving a clot-dissolving drug called tenecteplase directly into the brain artery can improve blood flow in stroke patients who still have blockages after standard mechanical clot removal. 156 adults with acute ischemic stroke were randomly assign…

This study looked at 65 people with advanced head and neck cancer that had spread to lymph nodes. It compared two approaches: having surgery to remove affected lymph nodes before chemo-radiation, versus chemo-radiation alone. The goal was to see if upfront surgery could reduce tr…

This study tested a new Swiss German speech test for children aged 4 to 6 with normal hearing. The goal was to find typical scores for how well kids hear single and double-syllable words, both in quiet and with background noise. The results will help doctors better assess hearing…

This trial tests whether placing vancomycin powder under the skin before closing a spinal fusion incision can reduce surgical site infections, which occur in up to 12% of such surgeries. Adults undergoing open spinal fusion will be randomly assigned to receive either the standard…

This study tested whether colchicine, an anti-inflammatory drug used for gout, can prevent new-onset atrial fibrillation and the need for a permanent pacemaker in people undergoing transcatheter aortic valve replacement (TAVI). About 120 older adults with severe aortic stenosis w…

This study tested whether giving clonidine, a blood pressure medication, before electroconvulsive therapy (ECT) could reduce the confusion and agitation that often follows the procedure. ECT is effective for severe depression and bipolar disorder, but up to 65% of patients experi…

This completed trial tested whether a combination of four non-opioid drugs (magnesium, dexmedetomidine, ketamine, and lidocaine) given during major surgery could improve patient recovery compared to standard opioid-only anesthesia. 240 adults undergoing planned major surgery were…

This study looks at whether adults aged 70 and older with multiple chronic conditions (but no heart disease) can safely stop taking statins. Researchers are comparing those who continue statins to those who stop, tracking deaths and major heart events over 2-4 years. The goal is …

This trial investigates whether a short stay at high altitude (up to 3,545 meters) is safe for people with asymptomatic moderate or severe aortic stenosis. Participants will undergo heart tests—including ECG, echocardiography, and exercise stress tests—both at low altitude and af…

This study looks at whether a person's expectations before a diagnostic nerve block influence how much pain relief they experience. Researchers will measure pain levels before and after the block and track changes over a week. The goal is to understand the role of expectations in…

This study tested whether injecting a fluorescent dye called indocyanine green (ICG) into the ureters helps surgeons see them more clearly during laparoscopic surgery for deep infiltrating endometriosis. 51 women with suspected or confirmed deep endometriosis took part. The goal …

This study used a special camera to measure how long natural fluorescent substances in the retina stay lit up after being excited by light. The goal was to see if these measurements can reveal areas of the retina under stress, like from poor blood flow. Nearly 900 healthy volunte…

This completed study followed 5 people with cystic fibrosis over two years to track COVID-19 antibodies from infection or vaccination. Researchers collected blood samples every six months to see how antibodies develop and last. The goal was to understand if people with CF have di…

This study used a special belt (electrical impedance tomography) to monitor lung function in 30 children aged 1 to 6 years during anesthesia for MRI scans. The goal was to see how much lung collapse occurs and how quickly it resolves after the procedure. The findings could help m…

This study looked at 150 colorectal cancer patients to see if counting tumor buds in biopsy samples could predict whether cancer has spread to lymph nodes or other organs. Researchers used a special stain to find tumor buds and counted them in the densest area. They then used a c…

This study looked at how being at high altitude (over 3,400 meters) affects the performance of highly trained medical rescuers. Twenty doctors performed simulated patient care scenarios at altitude, with and without extra oxygen, and after spending a night there. The goal was to …

This study tested whether healthy adults can learn to increase communication between brain regions using neurofeedback – a technique where they see real-time feedback of their brain activity. The goal was to see if this heightened brain communication could improve visual percepti…