New biopsy method may predict cancer spread without surgery
NCT ID NCT03336658
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 150 colorectal cancer patients to see if counting tumor buds in biopsy samples could predict whether cancer has spread to lymph nodes or other organs. Researchers used a special stain to find tumor buds and counted them in the densest area. They then used a computer model to estimate the risk of spread and survival. The goal was to standardize this method so doctors can better plan treatment without relying on surgery alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a standardized way to predict cancer spread and survival from biopsy samples, helping doctors plan treatment more accurately.
What could go wrong
This is an observational study, not a treatment trial. The prediction model was developed from past data and may not work perfectly in new patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of visceral surgery and transplant surgery, Berne University Hospital
Bern, 3010, Switzerland