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Pee test could spot colon cancer early in africa

NCT ID NCT07649057

Recruiting now Diagnosis Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new urine test that aims to detect colorectal cancer and precancerous polyps early. Researchers will enroll 210 people in Ghana, Tanzania, and South Africa who have symptoms like rectal bleeding or are getting a colonoscopy. The test uses a biosensor to find three specific substances in urine, and the goal is to see if it works as well as earlier results from Nigeria, which showed 90% accuracy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
3-metabolite biosensor (urine test)
What this could lead to
If successful, this could provide a simple, non-invasive urine test for early detection of colorectal cancer in Africa, improving survival rates.
What could go wrong
This is a validation study in specific African regions; results may not generalize elsewhere. The test's accuracy may be lower than hoped, and it is not yet a standard screening tool.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal carcinoma colorectal neoplasm Gastrointestinal Hemorrhage precancerous condition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER CRC PRECANCEROUS POLYP RECTAL BLEEDING

Contacts and locations

Locations

  • Kilimanjaro Christian Medical Centre (Data Collection Only)

    NOT_YET_RECRUITING

    Moshi, Tanzania

  • Korle Bu Teaching Hospital (Data Collection Only)

    NOT_YET_RECRUITING

    Accra, Ghana

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

  • Wits Donald Gordon Medical Centre (Data Collection Only)

    NOT_YET_RECRUITING

    Johannesburg, South Africa

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