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STREAM trial: should seniors ditch statins?

NCT ID NCT05178420

Completed Knowledge-focused Sponsor: Insel Gruppe AG, University Hospital Bern Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study looks at whether adults aged 70 and older with multiple chronic conditions (but no heart disease) can safely stop taking statins. Researchers are comparing those who continue statins to those who stop, tracking deaths and major heart events over 2-4 years. The goal is to provide clear guidance on when it's safe to discontinue statins in this population.

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Conditions

The condition(s) this trial relates to.

inherited lipid metabolism disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STATIN TREATMENT FOR PRIMARY PREVENTION

Contacts and locations

Locations

  • CHUV Lausanne

    Lausanne, Switzerland

  • Centre hospitalier Bienne

    Biel/Bienne, Canton of Bern, 2501, Switzerland

  • Clinic for General Internal Medicine, Bern University Hospital Bern

    Bern, 3010, Switzerland

  • HFR Fribourg

    Fribourg, 1752, Switzerland

  • Hospital Burgdorf

    Burgdorf, Switzerland

  • Hospital Langnau

    Langnau, Switzerland

  • Hospital St. Gallen (Geriatrics)

    Sankt Gallen, Switzerland

  • Hôpital La Tour

    Geneva, Switzerland

  • Hôpital Neuchâtelois

    Neuchâtel, Switzerland

  • Hôpitaux Universitaires de Genève (Geriatrics)

    Geneva, Switzerland

  • Hôpitaux Universitaires de Genève (Internal Medicine)

    Geneva, Switzerland

  • Kantonsspital Aarau

    Aarau, Switzerland

  • Kantonsspital Baden

    Baden, Switzerland

  • Kantonsspital Graubünden

    Chur, Kanton Graubünden, 7000, Switzerland

  • Kantonsspital Schaffhausen

    Schaffhausen, 8208, Switzerland

  • Klinik Barmelweid AG

    Barmelweid, Canton of Aargau, 5017, Switzerland

  • Leids Universitair Medisch Centrum

    Leiden, South Holland, 2333, Netherlands

  • Luzerner Höhenklinik Montana AG

    Crans-Montana, Valais, 3963, Switzerland

  • Ospedale Regionale di Bellinzona e Valli

    Bellinzona, Switzerland

  • Spital Limmattal

    Schlieren, Canton of Zurich, 8952, Switzerland

  • Stadspital Waid

    Zurich, Switzerland

  • Stadtspital Triemli

    Zurich, Switzerland

  • UNIVERSITY HOSPITAL CENTER of Bordeaux

    Bordeaux, Nouvelle Acquitaine, 33404 Talence Cedex, France

  • Universitätsspital Basel

    Basel, Switzerland

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