Weight-Loss drug may curb alcohol cravings in fatty liver patients

NCT ID NCT06546384

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether semaglutide (a GLP-1 drug used for diabetes and weight loss) can help people with obesity and fatty liver disease reduce or stop drinking alcohol. 64 participants will receive either semaglutide injections plus lifestyle counseling, or counseling alone. The main goal is to see if more people in the drug group achieve total alcohol abstinence after 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
semaglutide
What this could lead to
If it works, this could point toward a new way to help people with obesity and fatty liver cut down on alcohol.
What could go wrong
This is a small, early-stage trial with only 64 people. It may not show a clear benefit, and semaglutide can cause nausea and other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Bern

    Bern, 3010, Switzerland

More trials for these conditions

Other studies related to the condition(s) this trial covers.