Smart algorithm aims to tailor blood thinner use after stents

NCT ID NCT05732701

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a risk-score algorithm can safely personalize how long patients take dual antiplatelet therapy (two blood thinners) after getting a heart stent. About 2,788 participants will be assigned to either algorithm-guided or standard treatment duration. The goal is to reduce both bleeding and clotting complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dual antiplatelet therapy (aspirin plus a P2Y12 inhibitor such as clopidogrel or ticagrelor)

What this could lead to

If successful, this could provide a safer, personalized approach to blood thinner use after heart stent procedures, reducing both bleeding and clotting risks.

What could go wrong

This is a large but early-stage algorithm-based study; the score may not outperform standard care, and individual patient factors could still lead to unexpected bleeding or clotting events.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Cardiology, Bern University Hospital

    RECRUITING

    Bern, 3010, Switzerland

    Contact

  • UOC Cardiologia San Giovanni Addolorata Hospital

    RECRUITING

    Roma, 00184, Italy

    Contact Email: •••••@•••••

  • University Clinical Center of the Republic of Srpska

    RECRUITING

    Banja Luka, 78000, Bosnia and Herzegovina

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact