Laser zaps brain tumor regrowth without delaying key therapy

NCT ID NCT07616986

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a minimally invasive laser treatment for glioblastoma that regrows shortly after initial surgery, before standard radiotherapy and chemotherapy begin. The goal is to see if the laser can safely treat the regrowth without delaying the planned follow-up treatments. Only 12 adults with glioblastoma will participate, and the main focus is on whether the treatment schedule can be maintained.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Laser interstitial thermal therapy (LITT) - a minimally invasive procedure using heat from a laser to destroy tumor tissue
What this could lead to
If successful, this could offer a way to treat early glioblastoma regrowth without delaying standard radiotherapy and chemotherapy, potentially improving survival.
What could go wrong
This is a very small, early feasibility study with only 12 participants. The procedure carries risks like bleeding, infection, or brain swelling, and it may not improve outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dep. of Neurosurgery, Bern University Hospital

    RECRUITING

    Bern, 3010, Switzerland

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