Could a less strict diet improve life for adults with rare glycogen storage disease?

NCT ID NCT06852612

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether adults with glycogen storage disease type I (GSDI) can safely include more fructose and galactose in their diet. Currently, patients must avoid these sugars, which limits food choices. Researchers will give 20 adults either fructose alone or fructose plus galactose and measure changes in blood lactate, triglycerides, and uric acid. The goal is to see if relaxed dietary restrictions could improve quality of life without harming metabolic control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fructose and galactose (dietary supplements)

What this could lead to

If successful, this could show that adults with GSDI can safely include more fruits and dairy in their diet, improving food choices and quality of life.

What could go wrong

This is a small, early-phase study with only 20 participants, so results may not apply to everyone. The dietary changes could cause metabolic imbalances in some patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glycogen storage disease I

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital

    RECRUITING

    Bern, 3010, Switzerland

    Contact

  • Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich

    NOT_YET_RECRUITING

    Zurich, 8091, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••