END STAGE RENAL DISEASE

This study tested whether giving oral vitamin C to patients with kidney failure on regular dialysis could safely help control their anemia. It involved 60 patients to see if the vitamin could reduce the amount of a standard anemia medication (erythropoietin) they needed. The goal…

This early-stage study tested a single injection of an experimental drug called MK-2060 in people with advanced kidney disease. The main goals were to check the drug's safety, see how long it stays in the body, and measure its effect on blood clotting. Only 14 people with stage 4…

This study tested whether a simple hand grip exercise program could help dialysis fistulas develop properly and stay open longer. Patients on dialysis were randomly assigned to either do hand grip exercises with a special device for six weeks or receive standard care. Researchers…

This study tested two different training programs to make dialysis treatments safer for people with kidney failure. Researchers worked with 20 dialysis clinics to see if training healthcare teams or coaching patients could reduce dangerous drops in blood pressure during treatment…

This study monitored the safety of continued home use of the HemoCare dialysis system for people with end-stage kidney disease. It allowed 25 patients who had completed an earlier trial to keep using the home dialysis equipment while regulators reviewed it for market approval. Th…

This study tested a portable device called the Carry Life UF system for people doing peritoneal dialysis at home. It aimed to see if the device could remove more excess fluid from the body than a standard dialysis session by carefully adding glucose during treatment. The trial in…

This study tested whether kidneys from deceased donors infected with hepatitis C could be safely transplanted into patients without the virus. After the transplant, recipients received antiviral medication to clear the hepatitis C infection. Researchers compared the health of the…

This study tested whether trained transplant recipients, acting as 'navigators,' could help other kidney failure patients complete the many steps needed to get a transplant. It involved about 170 adult patients on dialysis, comparing those who received help from a navigator with …

This study tested a small, drug-releasing implant placed during surgery to create a dialysis access point (called a fistula). The goal was to see if the implant, compared to standard surgery, could help the fistula develop better and last longer for patients on kidney dialysis. A…

This study tested a new type of hemodialysis filter called ELISIO-HX. It aimed to check if the filter was safe for patients with kidney failure and if it could better remove certain waste products from the blood. The study involved 22 stable patients who were already on long-term…

This study tested whether a small, drug-releasing implant placed during surgery could improve the success of creating a usable dialysis access point (called a fistula) in the arm. It involved 269 people with kidney failure who needed to start or were recently on dialysis. Researc…

This study compared a new lab-made blood vessel against standard surgery for creating dialysis access in people with kidney failure. Researchers tested whether the engineered vessel works as well as the patient's own vein for connecting to dialysis machines. The goal was to provi…

This study tested whether an experimental drug called MK-2060 could prevent dangerous blood clots from forming in the artificial grafts used for dialysis in people with kidney failure. Over 500 participants received either one of two doses of the drug or a placebo to see which wo…

This study tested whether a special communication tool called 'Best Case/Worst Case' helps doctors have better conversations with older patients who have severe, permanent kidney failure. The tool helps doctors and patients talk about future care options, quality of life, and end…

This study tested whether a 26-week exercise and education program could help people on long-term dialysis feel better. Researchers compared 133 patients who either did the exercise program during their dialysis sessions or received standard care. The goal was to see if regular e…

This study tested a program called SPIRIT, designed to help patients with end-stage kidney disease and their chosen family members plan for difficult end-of-life care decisions. The program involved two guided conversations with a trained dialysis care provider. Researchers wante…

This study explored how kidney specialists think about involving patients in choosing their dialysis treatment. Researchers interviewed 25 active kidney doctors across Belgium to understand their beliefs, attitudes, and the challenges they face when discussing options like home d…

This study tested a new education program for patients waiting for a kidney transplant. The program teaches patients and their chosen friends or family members (called 'Live Donor Champions') about living kidney donation. The goal was to see if this program could be successfully …