END STAGE RENAL DISEASE

This study is tracking the long-term safety of an experimental cell therapy given to kidney transplant patients. The therapy, called CAR-Treg, is designed to help the body accept the new kidney and reduce rejection. Researchers will follow 11 patients for up to 15 years to monito…

This study is testing a new surgical technique for creating the blood vessel connection needed for dialysis. It compares a new, less invasive method to the standard surgery to see if it results in a more reliable and longer-lasting connection. The goal is to reduce the need for r…

This study is testing if adding a weekly blood-filtering treatment (hemoperfusion) to standard dialysis helps remove more harmful waste products from the blood of people with kidney failure. Researchers will measure levels of specific substances linked to complications and check …

This study is testing whether using a robot to assist with kidney transplant surgery leads to fewer complications than traditional open surgery. It involves 106 adult patients receiving a kidney transplant, who are randomly assigned to have either the robotic or the open procedur…

This study aims to find out if it's safe to stop long-term immune-suppressing drugs in patients with ANCA vasculitis who have developed total kidney failure. Researchers will compare patients who stop the drugs to those who continue them, checking for severe infections, disease f…

This study is testing the safety and performance of Medtronic's new Hugo robotic surgery system for urologic procedures, primarily for cancers of the bladder, prostate, and kidney. It will enroll 144 adult patients needing specific cancer surgeries to see if the robot can complet…

This study is testing whether a medication called nicorandil can help prevent serious heart problems in people who have both severe heart disease and kidney failure requiring dialysis. It will involve about 268 patients to see if taking the drug lowers their risk of heart attacks…

This study is testing a new synthetic tube, called the aXess graft, for patients with end-stage kidney disease who need hemodialysis but are not good candidates for the standard surgical connection (a fistula). The goal is to see if this new graft is safe and works well as a long…

This study aims to see if a simple urine test, originally developed for adults, can accurately detect early signs of rejection or infection in children who have received a kidney transplant. It involves 445 children and teens, aged 2 to 18, who have had a transplant. The goal is …

This study is testing a shorter, 1-month treatment to prevent latent tuberculosis (TB) from becoming active in people waiting for a kidney transplant. Researchers want to see if this shorter regimen is safe, if patients can complete it, and how the body processes the drugs. The g…

This study is testing a new online health platform designed to help people receiving hemodialysis. The platform provides education and support for exercise, nutrition, and mental well-being. Researchers want to see if using this holistic, virtual program can improve patients' phy…

This study is testing whether giving intravenous nutrition directly during dialysis treatments can help patients maintain muscle mass and improve their quality of life. Researchers are enrolling 166 people who receive regular hemodialysis for kidney failure. They will measure cha…

This study is testing whether a comprehensive education program helps veterans with advanced kidney disease understand their condition and treatment options better. It compares this special education to usual care to see if it leads to more informed choices about dialysis, partic…