15-Year watch begins for experimental transplant therapy

NCT ID NCT05987527

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 27 times

Summary

This study follows 11 kidney transplant patients who received an experimental cell therapy called TX200-TR101 in an earlier trial. Researchers will monitor them for up to 15 years to check for long-term side effects and how well their transplanted kidney is doing. The goal is to see if this personalized therapy is safe over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Erasmus MC, University Medical Center

    Rotterdam, Netherlands

  • Leiden University Medical Centre

    Leiden, Netherlands

  • Oxford University Hospitals NHS Foundation Trust

    Oxford, United Kingdom

  • University Hospitals Leuven

    Leuven, Belgium

  • University Medical Center Groningen

    Groningen, Netherlands

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TX200-TR101 (a personalized cell therapy using the patient's own modified immune cells)

What this could lead to

If successful, this could show that TX200-TR101 is safe over many years and may help reduce the need for lifelong anti-rejection drugs in kidney transplant patients.

What could go wrong

This is a small, early follow-up study (only 11 people) and does not test whether the therapy works. Long-term risks or side effects may still emerge.

Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.