New biodegradable graft could improve dialysis access for kidney patients

NCT ID NCT06494631

ENROLLING_BY_INVITATION Disease control Sponsor: Xeltis Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 30, 2026 · Updated 3 times

Summary

This study is testing a new type of graft (called aXess) for people with end-stage kidney disease who need hemodialysis but can't have a standard fistula. The graft is made of a biodegradable material that may help reduce complications. About 140 adults will be enrolled to see if the graft is safe and works well for dialysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Xeltis Hemodialysis Access (aXess) graft
What this could lead to: If successful, this graft could provide a safer, more durable option for hemodialysis access in patients who cannot have a standard fistula.
What could go wrong: This is an early-stage, single-arm study with no comparison group, so results may not be definitive. Risks include infection, bleeding, and graft failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

END-STAGE RENAL DISEASE

Contacts and locations

Locations

AKDHC Medical Research Services, LLC

Phoenix, Arizona, 85016, United States
AKDHC Medical Research Services, LLC

Tuscon, Arizona, 85718, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Flow Vascular, Surgery Specialty Hospitals of America

Pasadena, Texas, 77504, United States
Greenwood Leflore Hospital

Greenwood, Mississippi, 38930, United States
Sarasota Memorial Hospital

Sarasota, Florida, 34239, United States
Surgical Specialists of Charlotte

Charlotte, North Carolina, 28210, United States

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