New biodegradable graft could improve dialysis access for kidney patients

NCT ID NCT06494631

ENROLLING_BY_INVITATION Disease control Sponsor: Xeltis Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing a new type of graft (called aXess) for people with end-stage kidney disease who need hemodialysis but can't have a standard fistula. The graft is made of a biodegradable material that may help reduce complications. About 140 adults will be enrolled to see if the graft is safe and works well for dialysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Xeltis Hemodialysis Access (aXess) graft

What this could lead to

If successful, this graft could provide a safer, more durable option for hemodialysis access in patients who cannot have a standard fistula.

What could go wrong

This is an early-stage, single-arm study with no comparison group, so results may not be definitive. Risks include infection, bleeding, and graft failure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AKDHC Medical Research Services, LLC

    Phoenix, Arizona, 85016, United States

  • AKDHC Medical Research Services, LLC

    Tuscon, Arizona, 85718, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Flow Vascular, Surgery Specialty Hospitals of America

    Pasadena, Texas, 77504, United States

  • Greenwood Leflore Hospital

    Greenwood, Mississippi, 38930, United States

  • Sarasota Memorial Hospital

    Sarasota, Florida, 34239, United States

  • Surgical Specialists of Charlotte

    Charlotte, North Carolina, 28210, United States