Dialysis upgrade: can adding a filter remove more toxins?
NCT ID NCT05639010
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a special filter (hemoperfusion) to regular dialysis can better remove waste products like beta-2 microglobulin, parathyroid hormone, and C-reactive protein from the blood. About 410 adults with end-stage kidney disease on maintenance dialysis will be randomly assigned to standard dialysis or dialysis plus the extra filter once a week. The goal is to see if the combination improves toxin clearance, which could help manage the disease better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hemoperfusion device (KHA80) combined with hemodialysis
What this could lead to
If it works, this could lead to a better way to remove harmful substances from the blood in people on dialysis, potentially improving their health and quality of life.
What could go wrong
This is a mid-stage trial testing a device, not a new drug. The benefits may be modest, and the results might not apply to all dialysis patients. Risks include possible side effects from the added procedure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Changhai Hospital
Shanghai, Shanghai Municipality, 200433, China