Breakthrough trial aims to free kidney recipients from daily pills

NCT ID NCT04540380

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a conditioning regimen to make the recipient's immune system accept a donor kidney without needing lifelong anti-rejection medication. About 20 adults with kidney failure receiving their first transplant from a living donor will participate. The main goal is to check safety and see if temporary immune cell mixing can lead to long-term tolerance.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States