Could a single cell infusion replace lifelong Anti-Rejection drugs?

NCT ID NCT03726307

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests whether a single infusion of special immune cells (regulatory dendritic cells) from the kidney donor can help the recipient's body accept the new kidney with fewer side effects. 14 first-time kidney transplant recipients will receive the cells one week before surgery and be followed for two years. The main goal is to check safety, not yet to prove the treatment works.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pittsburgh, Starzl Transplantation Institute

    Pittsburgh, Pennsylvania, 15213, United States