Kidney patients needed for drug dosing study

NCT ID NCT06845813

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 study looked at how different levels of kidney function affect the way the body processes a single dose of the drug AZD6234. Researchers compared 24 adults with various degrees of kidney impairment to healthy volunteers. The goal was to understand how the drug moves through the body and whether it is safe, which will help guide future dosing recommendations for people with kidney disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AZD6234

What this could lead to

If successful, this study could help doctors determine the right dose of AZD6234 for people with kidney problems, making the drug safer and more effective for them.

What could go wrong

This is a very early (Phase 1) study with only 24 participants, so results may not apply to everyone. The drug's safety and effectiveness for treating any condition are not yet established.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

end stage renal failure impaired renal function disease kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Lake Forest, California, 92630, United States

  • Research Site

    Orlando, Florida, 32808, United States

  • Research Site

    Orlando, Florida, 32809, United States