Stem cell trick may let kidney patients ditch daily pills
NCT ID NCT00619528
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving donor stem cells and a drug called Campath-1H can help kidney transplant recipients stop taking anti-rejection medications permanently. Eighty-eight patients receiving a kidney from an identical sibling will get the stem cell infusions and temporary immunosuppression. The goal is to see if the body accepts the new kidney without needing lifelong drugs, with follow-up lasting up to 10 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- donor hematopoietic stem cells and Campath-1H
- What this could lead to
- If successful, this could allow kidney transplant recipients to stop taking lifelong immunosuppressive drugs without rejecting the new kidney.
- What could go wrong
- This is an early-stage study with only 88 participants, and not all patients may achieve drug-free tolerance. There are risks of infection, graft rejection, or side effects from the conditioning regimen.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States
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