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Can dialysis filters improve kidney recovery? a data review seeks answers

NCT ID NCT05282732

Knowledge-focused Sponsor: Fresenius Medical Care Deutschland GmbH Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This study looks back at treatment records from 119 people with kidney failure who underwent haemodialysis using Genius SleddFlux filters, Ultraflux AV 600 S filters, and Genius 90 concentrates. The goal is to assess how well these devices performed in acute and chronic dialysis patients, including those with unstable blood pressure. Researchers will examine daily lab values like urea and creatinine, as well as fluid removal volumes, to evaluate filter effectiveness and potential kidney function improvement.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Genius SleddFlux filter, Ultraflux AV 600 S filter, and Genius 90 concentrates used in haemodialysis
What this could lead to
If the analysis shows these filters work well, it could support their continued use in dialysis care and guide better treatment for kidney failure patients.
What could go wrong
This is a retrospective review of past records, not a controlled experiment. The data may be incomplete or inconsistent, and the results may not apply to all dialysis patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

119 people

The number who actually took part.

Started

Oct 2022

Finished

Oct 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Haemodynamically instable patients in acute haemodialysis and chronic haemodialysis patients treatment with the Genius system

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients with an indication for the extracorporeal blood treatment suffering from renal insufficiency who received all treatments, between January 2019 and December 2019, with the investigational devices have to be included in the study in chronological order. * For aHD patients: availability of at least 3 of the 5 primary variables (daily urea, creatinine, potassium, ultrafiltration and effluent volume) for 50 % of the documented treatments. * For cHD patients: availability of the ultrafiltration values for all treatments and at least one value for urea and creatinine per week Exclusion Criteria: * Simultaneous use of another filter/adsorber for another form of therapy

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Conditions

The condition(s) this trial relates to.

acute kidney injury chronic kidney disease chronic renal failure syndrome end stage renal failure kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute renal failure End stage renal disease Renal failure

Contacts and locations

Locations

  • BG Klinikum Unfallkrankenhaus Berlin gGmbH

    Berlin, 12683, Germany

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • Universitätsklinikum Jena

    Jena, 07743, Germany

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