ATRIAL FIBRILLATION

This study looked at 9 people with atrial fibrillation (AFib) that came back after an initial cryoballoon ablation. It compared two repeat ablation methods: another cryoballoon procedure versus radiofrequency ablation guided by a high-fidelity mapping system (Rhythmia). Participa…

This study tested whether giving a more powerful antiplatelet drug (prasugrel or ticagrelor) for one month after a heart attack, along with a standard blood thinner, could reduce heart attacks, strokes, and deaths in people with atrial fibrillation. The 602 participants were then…

This study tested whether a newer blood thinner, rivaroxaban (Xarelto), is as safe and effective as the older drug warfarin for preventing strokes in people who develop atrial fibrillation after heart surgery. About 100 adults who had open-heart surgery and then experienced a new…

This study tested whether a smartphone app that reminds patients to take their medication can improve how consistently people with atrial fibrillation take their blood thinner (rivaroxaban). Over 600 adults with AF and other health issues like high blood pressure or diabetes used…

This study tested a new way to treat paroxysmal atrial fibrillation (a type of irregular heartbeat) using pulsed field energy instead of standard radiofrequency. 292 adults with drug-resistant AF took part. The goal was to see if the new method is faster, safer, and more effectiv…

This study tested whether catheter ablation (a procedure to fix irregular heart rhythm) is better than standard rate-control medication for people with both atrial fibrillation and heart failure. Over 400 participants were randomly assigned to either ablation or medication. The m…

This study tested a new device called the Volt PFA System, which uses pulsed field ablation to treat atrial fibrillation (AF), a common heart rhythm problem. Researchers enrolled 392 people with symptomatic AF that didn't respond to medication. The goal was to see if the procedur…

This study tested a combination of two drugs, rivaroxaban and ticagrelor, in 40 patients with atrial fibrillation who had a stent placed. The goal was to see if this combo causes less bleeding and prevents heart attacks or strokes better than current treatments. Patients took the…

This study looked at 200 people with both heart failure and permanent atrial fibrillation. Participants received either a standard defibrillator (ICD) or one that also paces both lower heart chambers (CRT/ICD). The goal was to see if the extra pacing reduces heart size and improv…

This study looked at whether Vidaza, a drug used for acute leukemia, could also help treat atrial fibrillation (an irregular heartbeat). The idea was that Vidaza might reverse certain DNA changes that lower the activity of a gene important for heart function. Only one person took…

This study tested two new devices that use energy pulses to treat persistent atrial fibrillation (a type of irregular heartbeat). 89 adults who had not responded to medication received a heart ablation procedure. The goal was to see if the devices are safe and can stop abnormal h…

This early study tested whether placing a thin layer of human amniotic membrane on the heart during bypass surgery could reduce inflammation and prevent post-operative atrial fibrillation (an irregular heartbeat). Twenty-seven patients were randomly assigned to receive either the…

This study tested a new device called the OMNYPULSE catheter with the TRUPULSE generator to treat paroxysmal atrial fibrillation (a type of irregular heartbeat). The goal was to see if it is safe and effective at isolating the veins that carry blood from the lungs to the heart. 1…

This pilot study tested whether community pharmacists can manage blood thinner therapy for older adults (60+) with atrial fibrillation who are at high risk for stroke but not on optimal treatment. Fourteen participants received pharmacist-led care for 3 months, then were followed…

This study tested a device called Amplatzer Amulet that closes a small pouch in the heart (left atrial appendage) in people with atrial fibrillation. The goal was to see if it safely reduces stroke risk without long-term blood thinners. 104 adults at high stroke risk took part ac…

This study compares two types of ablation (pulsed-field vs cryoballoon) for treating atrial fibrillation in people with heart failure and reduced pumping function. Researchers looked back at 700 patients who had their first ablation to see which method works better and is safer. …

This study tested a device called the Lariat to close off a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who cannot take blood thinners. The goal was to reduce the risk of stroke. Nine participants were enrolled, and the study measured h…

This study looked at whether using a CPAP machine at night can reduce episodes of atrial fibrillation (a type of irregular heartbeat) in people who also have obstructive sleep apnea. Twenty-five adults with both conditions were enrolled. Half used CPAP while the other half were o…

This completed study tested a multi-discipline care program for 343 adults with atrial fibrillation. Led by an electrophysiologist, the team aimed to uncover hidden risk factors and improve treatment. Researchers monitored AF burden and major cardiovascular events like stroke and…

This study tested a new tool called VISITAG that helps doctors track where they apply heat during a heart procedure for atrial fibrillation (AFib). The goal was to see if it makes the procedure safer and more effective at preventing irregular heartbeats for a year. 200 adults hav…

This study tested a procedure to close a small pouch in the heart (left atrial appendage) in people with atrial fibrillation who are at high risk for both stroke and bleeding. The goal was to see if this procedure works better than standard blood-thinning medications at preventin…

This study tested a special catheter and generator system to treat people with paroxysmal atrial fibrillation (AFib), a condition where the heart beats irregularly. The goal was to safely isolate the veins that trigger AFib and restore normal rhythm. 135 participants were treated…

This study tested a new approach for repeat catheter ablation in people with atrial fibrillation (AF) whose symptoms returned after a previous ablation. Doctors used a special software algorithm (VX1) to guide the procedure. The study included 96 adults and measured how many stay…

This study looked at whether stopping coffee helps prevent atrial fibrillation (AFib) from returning after a heart shock treatment called cardioversion. Two hundred coffee drinkers with AFib were randomly assigned to either keep drinking coffee or avoid it for six months. Researc…

This study tested a procedure called left atrial appendage occlusion (LAAO) against standard blood-thinning medications in 81 people with atrial fibrillation who were also getting a new heart valve (TAVI). The goal was to see if LAAO could prevent strokes and bleeding better than…

This pilot study tested a procedure to close the left atrial appendage—a small pouch in the heart where clots often form—in 58 patients with atrial fibrillation who had a prior brain bleed and cannot take standard blood thinners. The goal was to see if this approach could reduce …

This study tracked 949 patients with non-valvular atrial fibrillation who received the WATCHMAN FLX Pro device, a small implant that closes off a part of the heart to reduce stroke risk. The goal was to see how well the device works in everyday medical practice, focusing on safet…

This study tested a device called the DiamondTemp system, which uses heat energy to destroy tiny areas of heart tissue causing irregular heartbeats in people with persistent atrial fibrillation. 376 adults with drug-resistant symptoms took part. The goal was to see if the procedu…

This phase 3 trial tested a special balloon catheter that uses radiofrequency energy to destroy tiny areas of heart tissue causing irregular heartbeats in people with symptomatic paroxysmal atrial fibrillation. The study enrolled 397 adults who had not responded to medication. Th…

This trial tested two blood thinners—rivaroxaban (Xarelto) and aspirin—in over 1,200 people with atrial fibrillation who had a successful ablation procedure. The goal was to see which one better prevents strokes and silent brain clots. Participants were followed for three years w…

This study tested whether sending mild electrical pulses just under the skin could help control heart rate in people with atrial fibrillation (AFib). 46 adults with symptomatic paroxysmal AFib who didn't respond to standard drugs were given a device implant. For two weeks, some r…

This study looked at whether metformin, a drug usually used for diabetes, can help prevent atrial fibrillation (an irregular heartbeat) from coming back after a standard procedure called catheter ablation. About 117 non-diabetic adults with a higher body weight took metformin or …

This study tested two different defibrillator waveforms—Zoll's 200J rectilinear biphasic shock and Lifepak's 360J biphasic truncated exponential shock—to see which restores normal heart rhythm better in people with atrial fibrillation. Over 500 adults were randomly assigned to re…

This completed study in Algeria followed 398 adults with atrial fibrillation who were taking the blood thinner Trombix (Rivaroxaban). The goal was to see how safe and effective the drug is in everyday medical practice, and how it affects quality of life. Researchers tracked serio…

This study tested whether a device called WATCHMAN FLX, which closes a small pouch in the heart, is a good alternative to blood thinners for preventing strokes in people with atrial fibrillation (AF) after a heart procedure called ablation. About 1,600 high-risk patients were enr…

This study tested a new mapping feature (FARAVIEW™) used with a pulsed field ablation catheter (FARAWAVE NAV™) to treat atrial fibrillation. Fifty patients with symptomatic AFib that didn't respond to medication were included. The goal was to see how well doctors could isolate th…

This study compared two treatments for persistent atrial fibrillation (an irregular heartbeat): cryoablation (freezing tiny areas of heart tissue) and antiarrhythmic drugs. 196 patients were randomly assigned to one treatment and monitored for over a year. The goal was to see whi…

This study tested a device called the Laminar Left Atrial Appendage Closure System in 29 people with atrial fibrillation who cannot take blood thinners. The device is implanted to seal off a small pouch in the heart where clots often form. The goal was to see if it is safe and ef…

This study tested two ways to treat persistent atrial fibrillation (a type of irregular heartbeat) using catheter ablation. In one group, doctors aimed to stop the abnormal rhythm during the procedure. In the other, they followed a preset plan and used electrical shock if needed.…

This study tested a procedure called cryoballoon ablation in 1,420 people with atrial fibrillation (an irregular heartbeat) and severe heart failure. The goal was to see if freezing the veins that trigger the irregular rhythm could reduce recurrence of the heart rhythm problem an…

This study tested whether a tailored ablation approach, which targets specific abnormal areas in the heart, works better than the standard anatomical ablation for people with persistent atrial fibrillation (AFib). 377 adults with AFib that didn't respond to medication were includ…

This study tested how well a small, portable device (LumiraDx) measures blood clotting (INR) compared to standard lab tests. Researchers collected blood from 420 adults, some taking warfarin and some not, using both a fingerstick and a vein draw. The goal was to see if the device…

This study tested whether two wearable devices—the Apple Watch and the Skylab CART-I ring—can accurately detect atrial fibrillation and other irregular heart rhythms compared to the standard 12-lead ECG. Researchers recruited 500 adults from UK cardiology clinics. Each participan…

This study tested whether a simple scoring system (ATE score) can safely rule out dangerous blood clots in the heart before a procedure for atrial fibrillation. Over 3,000 adults participated. The goal was to see if the score could replace a more uncomfortable ultrasound test, po…

This study tested whether a Withings device (BeamO with ECG app) can accurately detect atrial fibrillation, a common heart rhythm problem. Over 370 adults each had a 30-second ECG with the device and a standard 12-lead ECG for comparison. The goal was to see how well the device i…

This study tested a new device called Masimo INVSENSOR00057 that records a single-lead ECG, similar to a standard lead I. Researchers compared its heart rate and atrial fibrillation detection against standard measurements in 365 adults, including healthy people and those with AFi…

This study tested whether an Apple Watch can detect atrial fibrillation (a heart rhythm problem) faster than usual methods in people aged 65 and older with high stroke risk. Over 400 participants wore the watch, which uses light sensors and an ECG to check heart rhythm. The goal …

This study tested whether a low-dose infusion of landiolol, a short-acting beta-blocker, could prevent atrial fibrillation in 400 non-Asian patients after cardiac surgery. Participants received either landiolol or a placebo for up to 48 hours after surgery. The goal was to see if…

This study tested whether an 8-week cardiac rehabilitation program using a stationary bike could improve cardiorespiratory fitness in 20 adults with atrial fibrillation. Participants exercised for 6 minutes, three times a week. The goal was to see if exercise capacity could incre…

This study tested whether a commercial meal replacement weight loss programme could reduce atrial fibrillation (AF) symptoms in overweight adults aged 60-85 with persistent AF. 119 participants were randomly assigned to either the weight loss programme or usual care for 32-36 wee…

This study tested whether showing patients with atrial fibrillation (AF) simple visual charts of common post-ablation symptoms could help them decide more confidently about undergoing the procedure. 75 adults with symptomatic AF who were considering catheter ablation used these d…

This study tested a short mindfulness and exposure therapy program in 13 adults with atrial fibrillation who also had high anxiety sensitivity. The goal was to see if the therapy could reduce heart-related anxiety, symptom burden, and AFib episodes. Participants attended 4-5 indi…

This study tested a remote magnetic catheter ablation technique for treating atrial fibrillation, a common heart rhythm problem. Researchers followed 804 patients to see how safe the procedure was, how much radiation it used, and how well it worked. The goal was to improve routin…

This study looks at medical records from France to see how doctors prescribe blood thinners to people with atrial fibrillation (an irregular heartbeat) who also have a high risk of stomach bleeding. The goal is to understand which treatments are used and how often serious bleedin…

This pilot study looked at whether it's possible to run a larger trial comparing two types of exercise—moderate steady exercise and high-intensity interval training—on symptoms of atrial fibrillation (AF), a common heart rhythm problem. Researchers enrolled 25 men and women with …

This study follows 340 people with atrial fibrillation who are having their first ablation procedure. Researchers will track heart rhythm using remote monitoring, along with imaging and blood tests, to find which factors—like patient health, heart structure, or electrical signals…

This study looked at 70 people aged 75 and older with atrial fibrillation who were taking a Xaban blood thinner (dabigatran, rivaroxaban, or apixaban) during an unplanned hospital stay. Researchers wanted to see if certain clinical or lab factors were linked to higher drug levels…

This study looked at over 2,100 patients aged 80 and older with atrial fibrillation who were taking the blood thinner warfarin. Researchers wanted to see if having multiple other health conditions (comorbidities) made it harder to keep their blood thinning levels stable. The goal…

This study tracked 883 adults with atrial fibrillation to see how consistently they took their direct oral anticoagulants (blood thinners). Researchers used pharmacy refill records and a simple questionnaire to measure adherence. The goal was to find patterns that could help iden…

This study enrolled 91 people with atrial fibrillation to see if computer simulations can identify the main electrical problem causing their irregular heartbeat. Participants had heart imaging, mapping, and symptom tracking before and after a standard ablation procedure. The goal…

This study measured how two common blood thinners (rivaroxaban and apixaban) behave in 193 adults with active cancer who also had blood clots or atrial fibrillation. Researchers aimed to understand factors like age, weight, and kidney function that affect drug levels. The goal wa…

This study looks at 250 people with atrial fibrillation who are having a hybrid ablation procedure. Researchers want to find out which factors—like clinical history, blood markers, and genetics—are linked to the procedure failing. The goal is to create a risk profile that helps d…

This study tested a new catheter designed to measure the heart's electrical signals in people with irregular heartbeats (atrial fibrillation, ventricular fibrillation, or junctional tachycardia). Researchers enrolled 42 adults to see if the device could better identify abnormal e…

This study collected medical and social information from 111 patients having their first ablation for atrial fibrillation, a common heart rhythm problem. Researchers wanted to understand how factors like income, education, location, and ethnicity might affect who receives this tr…

This study gathered information from routine medical care for 198 adults with atrial fibrillation who had a prior procedure to close a small heart pouch (left atrial appendage occlusion) and later needed a heart ablation. Researchers looked at patient details, procedure steps, bl…

This study aimed to create a new questionnaire that measures how atrial fibrillation (AF) affects a person's quality of life. Researchers worked with 206 adults who have AF to develop and test this tool. The goal was to better understand the real-world impact of AF beyond just me…

This study looked at 155 people with early-onset atrial fibrillation to see if genetic testing can help doctors choose better treatments. Participants had heart imaging and ECG tests to find hidden heart muscle or rhythm disorders. The goal is to learn how genetics influence the …

This study tracked 1,826 people who received a small implantable heart monitor (Confirm Rx) to check for irregular heartbeats. Over 12 months, researchers recorded how often the device caused serious problems and how well it worked in daily life. The goal was to see if the monito…

This study looked at 200 people with atrial fibrillation to see if treatments like catheter ablation or exercise training change levels of a brain chemical called BDNF. Researchers also checked if these changes relate to mood and quality of life. The goal was to gather knowledge,…

This study tested a 12-week virtual education program for primary care providers in North Carolina to improve how they manage atrial fibrillation (AFib). 70 providers joined online sessions to learn about AFib care and EKG interpretation. Researchers measured changes in provider …

This study tested a six-session virtual education program called 'AF at Home' for adults with atrial fibrillation. Participants attended Zoom classes over three weeks to learn about self-monitoring and managing their condition. The goal was to see if the program improved quality …

This completed study looked at 309 adults with heart failure to see if increased pressure in the brain is linked to atrial fibrillation (an irregular heartbeat). Researchers measured eye nerve sheath diameter as a sign of brain pressure and used echocardiography to check heart fu…

This study looked at whether sending alerts to pharmacists instead of doctors helps improve how blood thinners (anticoagulants) are prescribed. Researchers tested two types of alerts with 306 healthcare providers. The goal was to see which method leads to faster and safer prescri…

This study looked at 44 people with persistent atrial fibrillation who had a second heart procedure 2 months after their first ablation. Doctors checked for reconnections in the pulmonary veins and treated them again to see if this improves outcomes. The goal was to better unders…

This small pilot study explored whether advanced heart imaging can detect hidden strokes in people who have never had atrial fibrillation but are at high risk due to conditions like diabetes or heart failure. Researchers used brain MRIs to find silent, symptom-free strokes and li…

This study followed 167 people with atrial fibrillation or flutter who had a catheter ablation procedure. Researchers measured changes in stroke and bleeding risk scores before and 3, 6, and 12 months after ablation. They also compared different monitoring methods, including impl…

This study looked at 91 Chinese patients with atrial fibrillation who had a stroke while taking blood thinners (NOACs). The goal was to understand why these strokes happen and whether not taking the medication as prescribed played a role. Researchers hope this knowledge will help…

This study tested two heart monitoring methods in 516 people who had a transient ischemic attack (TIA or mini-stroke). The goal was to see which method better detects hidden atrial fibrillation, a heart rhythm problem that raises stroke risk. Participants received either a small …

This study tested a new imaging system called VERAFEYE in 18 people already scheduled for standard heart procedures like ablation or closure. Doctors used the device during the procedure and gave feedback via a questionnaire. The goal was to gather information to improve the syst…

This study tested whether a computer program (Clinical Decision Support System) helps doctors follow official treatment guidelines for patients with both high blood pressure and atrial fibrillation (an irregular heartbeat). Researchers compared clinics using the program to those …

This completed study tested a new algorithm that automatically measures the cycle length and complexity of atrial fibrillation (AF) signals during a heart ablation procedure. Researchers collected data from 21 people with persistent AF undergoing ablation. The goal was to see if …

This study aimed to find the best marker for measuring how well heart rate is controlled in people with atrial fibrillation. Researchers tested 13 adults using exercise tests with different doses of heart rate medication. The goal was to see which marker best reflects rate contro…

This study looked at 80 people having a heart procedure called ablation to treat irregular heartbeats. Doctors wanted to see if a CT scan could accurately show the location of a nerve near the heart that can be accidentally injured. They compared the CT images with a standard met…

This completed study analyzed data from over 2 million people in France with atrial fibrillation (an irregular heart rhythm) to compare outcomes between those who took blood thinners and those who did not. Researchers looked at rates of stroke, major bleeding, and death between 2…

This study gathered information from 100 people undergoing a standard heart procedure called left atrial appendage closure. Researchers used the data to test a software tool that measures heart structures from echocardiograms. No new treatments or procedures were given—only routi…

This study looked at 175 adults with atrial fibrillation who had radiofrequency ablation. Researchers wanted to see if a special map of the heart's electrical signals (called an isochron map) could predict whether patients would stay free of atrial fibrillation 18 months later. T…

This study tested a larger 31 mm cryoballoon in 20 patients with paroxysmal atrial fibrillation to see how much heart tissue it could freeze. Researchers used 3D maps before and after the procedure to measure the size of the treated area. The goal was to gather data to improve fu…

This study looked at over 12,500 people in Korea with atrial fibrillation (an irregular heartbeat) to see how their condition and health outcomes changed over time. Researchers used existing hospital and national insurance records, not new patient visits. The goal was to better u…

This study looked at how safe and effective the blood thinner edoxaban is for preventing strokes in people aged 80 or older with a common heart rhythm problem called atrial fibrillation. Researchers followed over 1,200 patients in Korea who were already prescribed edoxaban by the…

This study followed 50 atrial fibrillation patients for 12 months to see if advanced heart imaging and ECG tests can predict whether the drug flecainide will keep their heart in normal rhythm. Researchers collected data during four clinic visits and analyzed it against outcomes l…

This study looked at two ways to assign care coordinators to older adults (65+) with heart disease or risk factors. One method used patients' own reports of difficulty coordinating care, while the other used usual triggers like hospital discharge. The goal was to see which approa…