ATRIAL FIBRILLATION

This study looked at whether adding a special pacemaker (called biventricular pacing) to an implantable defibrillator can help people who have both permanent atrial fibrillation and heart failure. The goal was to see if this treatment could shrink an enlarged heart, improve its p…

This study looked at a new combination of two blood thinners (rivaroxaban and ticagrelor) for people with atrial fibrillation who had a heart stent placed. The goal was to see if this combo causes less bleeding than the standard three-drug therapy, while still preventing heart at…

This study tested a new tool called VISITAG that helps doctors perform heart ablation more precisely for people with a type of irregular heartbeat called paroxysmal atrial fibrillation. 200 patients having their first ablation were included. The goal was to see if the tool made t…

This study tested a procedure called left atrial appendage occlusion (LAAO) against standard blood-thinning medications in 81 people with atrial fibrillation who were getting a new heart valve (TAVI). The goal was to see if LAAO could prevent strokes and bleeding better than drug…

This study tested a new tool called the DiamondTemp Ablation System for people with persistent atrial fibrillation (a type of irregular heartbeat). The goal was to see if it could safely restore a normal heart rhythm and keep it that way for at least a year. 376 adults with persi…

This study tested a new way to treat paroxysmal atrial fibrillation (a type of irregular heartbeat) using pulsed field energy instead of standard radiofrequency. 292 adults with drug-resistant symptoms took part. The goal was to see if the new method is faster, safer, and more ef…

This study tested whether closing off a small part of the heart (the left atrial appendage) with the WATCHMAN FLX device is a safe and effective alternative to taking daily blood thinners after a common heart procedure for atrial fibrillation. It involved 1600 high-risk patients.…

This study tested a device called the Lariat to close a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who are at risk for stroke but cannot take blood thinners. Nine participants underwent the procedure to see if it could safely and effec…

This study looked at 411 people with both heart failure and atrial fibrillation (a fast, irregular heartbeat). It compared two approaches: using a catheter to burn small areas in the heart to restore normal rhythm, versus simply controlling the heart rate with medication. The goa…

This study tested two treatments for people with persistent atrial fibrillation (a type of irregular heartbeat that lasts for weeks). One treatment uses a special balloon to freeze small areas in the heart (cryoablation), and the other uses standard heart rhythm medications. The …

This study looked at whether metformin, a common diabetes medication, can reduce the return of irregular heartbeats in people with atrial fibrillation who undergo a heart procedure called ablation. 117 participants were randomly assigned to receive metformin or no additional trea…

This study looked at 700 people with both atrial fibrillation (an irregular heartbeat) and heart failure (a weak heart pump). It compared two catheter-based treatments that isolate the veins carrying abnormal signals to the heart: a newer method called pulsed-field ablation and a…

This study tested two new devices that use electrical pulses to treat persistent atrial fibrillation, a type of irregular heartbeat. 89 adults who had not responded to medication took part. The goal was to see if the procedure is safe and can stop the abnormal signals causing the…

This study tested the WATCHMAN FLX Pro device in 949 people with non-valvular atrial fibrillation who are at risk for stroke and bleeding. The device is implanted to close off a part of the heart where clots often form, aiming to reduce stroke risk without needing lifelong blood …

This study looked at 1,284 people with atrial fibrillation (AF) who had a successful procedure to fix their irregular heartbeat. The goal was to find the best way to prevent strokes after the procedure. Researchers compared taking a daily blood thinner (anticoagulant) versus taki…

This study tested a remote magnetic catheter ablation technique for treating atrial fibrillation, a common heart rhythm problem. Over 800 patients were observed to see if the procedure is safe, reduces radiation exposure, and effectively controls the condition. The approach uses …

This study looked at a procedure to close a small pouch in the heart (the left atrial appendage) in people with an irregular heartbeat (atrial fibrillation) who have already had a brain bleed. Because blood thinners, the usual stroke prevention, are too risky for these patients, …

This study tested a device called the Amplatzer Amulet that closes a small pouch in the heart (left atrial appendage) in people with atrial fibrillation who are at high risk for stroke. The goal was to see if the device is safe and works well over time. 104 adults from Southeast …

This study looked at whether a procedure called cryoballoon ablation (freezing the veins near the heart) can safely and effectively treat atrial fibrillation (an irregular heartbeat) in people who also have severe heart failure. About 1,420 adults with symptoms and a weak heart p…

This study tested a new system that uses targeted electrical pulses to treat atrial fibrillation (AFib), a common heart rhythm problem. 392 people with symptomatic AFib that didn't improve with medication received the procedure. The goal was to see if the system is safe and can r…

This study looked at whether using a CPAP machine at night can reduce episodes of atrial fibrillation (an irregular heart rhythm) in people who also have obstructive sleep apnea. Researchers measured changes in heart rhythm, heart size, quality of life, and hospital visits in 25 …

This study looked at whether sending mild electrical pulses just under the skin could help people with atrial fibrillation (a type of irregular heartbeat) feel better by keeping their heart rate under control. A total of 46 adults with symptomatic paroxysmal AF who did not respon…

This study tested a procedure to close a small pouch in the heart (left atrial appendage) in people with atrial fibrillation who are at high risk for both stroke and bleeding. The goal was to see if this approach is safer and more effective than standard blood-thinning medication…

This study tested whether a personalized ablation approach, which targets specific problem areas in the heart, works better than the standard method for treating persistent atrial fibrillation (AFib). 377 adults with AFib were randomly assigned to either the tailored or standard …

This study looked at how well the blood thinner edoxaban works and its safety in people aged 80 and older with a type of irregular heartbeat called atrial fibrillation. The goal was to see if it helps prevent strokes and serious bleeding. Over 1,200 older adults in Korea took par…

This early-phase study tested whether placing a human amniotic membrane (a natural tissue from childbirth) on the heart during bypass surgery could reduce inflammation and prevent a common complication called atrial fibrillation. 27 adults having their first bypass surgery were r…

This study looked at whether a team of heart specialists working together can help people with atrial fibrillation better manage their condition. Over 300 adults with AF were enrolled to receive coordinated care led by an electrophysiologist. The goal was to find hidden risk fact…

This study looked at whether Vidaza, a drug used for acute leukemia, could also help treat atrial fibrillation (an irregular heartbeat). The idea was that Vidaza might reverse certain DNA changes that lower the activity of a gene important for heart function. Only one person took…

This study tested a special balloon catheter that uses radiofrequency energy to treat people with a heart rhythm problem called paroxysmal atrial fibrillation (AFib). The device aims to safely and effectively stop AFib episodes by creating small scars in the heart to block faulty…

This study tested a new mapping feature (FARAVIEW) used with a special catheter (FARAWAVE NAV) to treat atrial fibrillation, a common heart rhythm problem. 50 adults with symptomatic AFib participated. The goal was to see how well the technology helped doctors isolate and treat t…

This study tested a special catheter and generator system to treat people with paroxysmal atrial fibrillation (AFib), a condition that causes irregular heartbeats. The treatment uses heat energy to isolate the veins that trigger AFib. 135 participants who did not respond to medic…

This study tested whether a computer program (Clinical Decision Support System) helps doctors better follow official treatment guidelines for patients with both high blood pressure and atrial fibrillation (an irregular heartbeat). About 282 adults took part, with some doctors usi…

This small pilot study tested whether community pharmacists can help older adults (over 60) with atrial fibrillation (AFib) take the correct blood-thinning medication to prevent strokes. Fourteen participants received pharmacist-led management for 3 months, with a 9-month follow-…

This study tested a new computer algorithm (VX1) to guide repeat catheter ablation in 96 people with atrial fibrillation (AF) whose previous ablation didn't work. The goal was to see if the tailored approach could keep patients free from AF episodes lasting more than 30 seconds f…

This study tested a new device (OMNYPULSE catheter with TRUPULSE generator) to treat paroxysmal atrial fibrillation, a type of irregular heartbeat. 188 participants received the procedure to isolate the lung veins. The study measured safety (side effects within 7 days) and effect…

This study tested a device called the Laminar Left Atrial Appendage Closure System in 29 adults with non-valvular atrial fibrillation (AFib) who cannot take or want an alternative to blood thinners. The device is meant to close off a small pouch in the heart where clots often for…

This study tested two different approaches to treat persistent atrial fibrillation (a type of irregular heartbeat) using a procedure called catheter ablation. 480 adults who had not had success with medication were randomly assigned to either stop the irregular rhythm during the …

This study tested whether a simple scoring system (ATE score) can safely rule out dangerous blood clots in the heart before a procedure to treat atrial fibrillation. Over 3,000 adults scheduled for catheter ablation were checked using both the ATE score and a standard ultrasound.…

This study looked at 516 people who had a transient ischemic attack (TIA or mini-stroke) to find the best way to detect atrial fibrillation (AF), a heart rhythm problem that raises stroke risk. Participants were monitored with a 24-hour ECG, a 28-day wearable ECG patch, or a smal…

This study tested how well a Withings device and its app can automatically detect atrial fibrillation (AFib), a common heart rhythm problem. 373 adults aged 22 and older used the device, and its readings were compared to a standard 12-lead ECG. The goal was to see how sensitive a…

This study checked how well a new ECG device (Masimo INVSENSOR00057) measures heart rate and detects atrial fibrillation (AFib). It included 365 adults—some healthy and some with known AFib. The device was compared to standard measurements to see if it works accurately.

This study tested whether an Apple Watch can help detect atrial fibrillation (a type of irregular heartbeat) faster in people at high risk. 436 adults aged 65 and older with no prior diagnosis of the condition wore an Apple Watch to monitor their heart rhythm. The goal was to see…

This study tested whether a low-dose drug called landiolol can prevent atrial fibrillation (a type of irregular heartbeat) in 400 non-Asian adults after heart surgery. Atrial fibrillation is common after such operations and can lead to complications. The drug was given as a conti…

This study tested whether a dietary weight loss and behavioral support program could reduce symptoms of atrial fibrillation (AF) in overweight adults aged 60 to 85. Participants were randomly assigned to either the weight loss program or usual care for about 8 months. The main go…

This small study tested a mindfulness and exposure therapy program in 13 adults with atrial fibrillation (an irregular heartbeat) who also had high anxiety sensitivity. The goal was to see if the program could reduce heart-related anxiety, symptom burden, and AFib episodes. The a…

This study tested whether showing patients with atrial fibrillation (AF) simple visual charts about common post-ablation symptoms helps them make more confident treatment decisions. 75 adults with symptomatic AF who were considering catheter ablation used these decision aids duri…

This study tested two different defibrillator waveforms (Zoll's 200J shock vs. Lifepak's 360J shock) to see which one better restores normal heart rhythm in people with atrial fibrillation. Over 500 adults participated, and the main goal was to check heart rhythm one minute after…

This study tested whether a special heart map (isochron map) can predict if atrial fibrillation returns after radiofrequency ablation. Researchers followed 175 adults with atrial fibrillation for 18 months after the procedure. The goal was to see if the map could identify who wou…

This study looked at 200 people with atrial fibrillation to see how two treatments—catheter ablation or exercise training—change levels of a brain chemical called BDNF. Researchers also checked if these changes relate to depression, quality of life, and symptoms. The goal was to …

This study looked at 44 people with persistent atrial fibrillation (an irregular heartbeat) who had a second heart procedure 2 months after their first ablation. Doctors checked for reconnections in the treated areas and fixed them to improve treatment. They also measured heart s…

This study observed 398 adults with atrial fibrillation in Algeria who were taking the blood thinner Trombix® (Rivaroxaban). Researchers tracked serious bleeding events and quality of life to see how the drug performs in real-world settings. The goal was to gather practical safet…

This study looked at why some people with a type of heart failure (HFpEF) develop an irregular heartbeat called atrial fibrillation (AF). Researchers measured fluid pressure in the heart and used a noninvasive eye scan to estimate pressure inside the skull. They found that higher…

This study gathered information from 100 adults undergoing a standard heart procedure to help evaluate a software tool that analyzes echocardiograms. No new treatments or tests were given—only routine care data was used. The goal was to see how well the software measures parts of…

This study looked at two methods for assigning care coordinators to older adults (65+) with heart disease or risk factors like diabetes and high blood pressure. The goal was to see which approach better prevented emergency room visits and hospitalizations. Researchers compared as…

This study followed 1,826 people who already needed a small heart monitor (Confirm Rx) to check for irregular heartbeats. Researchers collected real-world data over 12 months to see how safe and well the device worked. The goal was to confirm its performance and meet European req…

This study tested whether sending safety alerts to pharmacists instead of doctors leads to faster changes in blood thinner prescriptions. Researchers enrolled 306 healthcare providers and compared how quickly each group responded to alerts. The goal was to find the best way for d…

This study looked at health records of over 2 million people in France with atrial fibrillation (an irregular heartbeat) to compare those who took blood thinners and those who did not. Researchers tracked strokes, major bleeding, and deaths between 2016 and 2020. The goal was to …

This study tested a 12-week virtual education program for primary care providers in North Carolina to improve their knowledge and confidence in managing atrial fibrillation (AFib). Researchers measured whether providers prescribed the right blood thinners to prevent strokes and w…

This study tested a new computer algorithm that automatically measures heart signal patterns during a procedure to treat atrial fibrillation (an irregular heartbeat). Researchers collected data from 21 adults undergoing ablation to see if the algorithm works well. The goal is to …

This study created a new questionnaire called AF-PROMS to measure how atrial fibrillation (AF) affects a person's quality of life. Researchers worked with 206 adults who have AF to develop and test the scale. The goal was to better understand the day-to-day impact of AF, not to t…

This study looked at whether stopping coffee drinking can reduce the chance of atrial fibrillation (an irregular heartbeat) returning after a procedure called cardioversion. About 200 adults who drank at least one cup of coffee daily were randomly assigned to either quit or keep …

This study looked at 155 people with early-onset atrial fibrillation to see if genetic testing could find inherited heart conditions. Participants had heart scans and tests to check for hidden problems. The goal was to learn how genetics affect treatment and care.

This study followed 167 adults with atrial fibrillation or flutter who had a catheter ablation procedure. Researchers measured changes in stroke and bleeding risk scores before and 3, 6, and 12 months after ablation. They also compared different ways to monitor heart rhythm after…

This study aimed to find the best marker for measuring how well heart rate is controlled in people with atrial fibrillation. Researchers tested 13 adults using exercise tests with different drug doses. The goal was to improve how doctors assess treatment success.

This study looked at 50 adults with atrial fibrillation (AF) who were starting the drug flecainide. Researchers used special heart ultrasound and ECG tests to see if they could predict who would stay in normal rhythm and who might have side effects. The goal is to replace the cur…

This study looked at over 12,500 people in Korea with atrial fibrillation (an irregular heartbeat) to see how their condition and health outcomes changed over time. Researchers used existing hospital and national insurance records, so no new patients were enrolled. The goal was t…

This small pilot study tested whether advanced heart imaging can identify people at high risk for embolic stroke even if they don't have atrial fibrillation. Researchers used brain MRIs to look for silent strokes in 5 participants with risk factors like diabetes or heart failure.…

This study tested a new imaging system called VERAFEYE in 18 adults already scheduled for a standard heart procedure (like ablation or closure). The goal was to collect doctors' feedback on how well the system works, not to prove it is safe or effective. Results will help improve…

This study aimed to measure how much heart tissue a new, larger freezing balloon catheter could treat during a standard procedure for atrial fibrillation (AFib). Researchers used detailed 3D heart maps before and after the procedure in 20 patients with intermittent AFib to measur…