Weight loss programme may ease heart symptoms in seniors with AF

NCT ID NCT03713775

Completed Symptom relief Sponsor: University of Oxford Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a commercial meal replacement weight loss programme could reduce atrial fibrillation (AF) symptoms in overweight adults aged 60-85 with persistent AF. 119 participants were randomly assigned to either the weight loss programme or usual care for 32-36 weeks. The main goal was to see if symptoms improved, measured by a standard AF symptom questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: meal replacement weight loss programme
What this could lead to: If successful, this weight loss programme could offer a simple, non-drug way to ease AF symptoms in older adults.
What could go wrong: This is a small, early-stage trial (119 participants) with no blinding. Results may not apply to all AF patients, and weight loss can be hard to maintain long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION OVERWEIGHT AND OBESITY

Contacts and locations

Locations

Oxford Centre for Magnetic Resonance (OCMR)

Oxford, Oxfordshire, OX3 9DU, United Kingdom

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